Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27550587 | 0.86 | MAPT (0.39) | KDM4ETSHRCA1CA2CA12 | |
| SCHEMBL3217575 | 0.85 | NPSR1 (0.38) | KDM4ECA1CA2CA9MAPT | |
| SCHEMBL3218236 | 0.81 | TSHR (0.43) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL5891669 | 0.81 | KDM4E (0.35) | KDM4ETSHRMAPTHDAC3HDAC4 | |
| SCHEMBL3219800 | 0.80 | TSHR (0.42) | KDM4ETSHRCA1CA2CA12 | |
| SCHEMBL27546956 | 0.78 | TSHR (0.40) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL3219726 | 0.78 | TSHR (0.40) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL3212013 | 0.77 | TSHR (0.42) | KDM4ETSHRCA1CA2CA12 | |
| SCHEMBL7034524 | 0.76 | MAPT (0.42) | KDM4EMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL7031283 | 0.73 | KDM4E (0.50) | KDM4ETSHRCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625841-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2009-12-01 | — | — | US | disclosed |
| US-7625841-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2009-12-01 | — | — | US | disclosed |
| US-7625841-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2009-12-01 | — | — | US | disclosed |
| EP-1443822-B1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| US-20080269061-A1 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269061-A1 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269061-A1 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
| US-7410933-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER CROPSCIENCE AG (DE) | 2008-08-12 | — | — | US | disclosed |
| US-7410933-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER CROPSCIENCE AG (DE) | 2008-08-12 | — | — | US | disclosed |
| US-7410933-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER CROPSCIENCE AG (DE) | 2008-08-12 | — | — | US | disclosed |
| CN-1324964-C | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER CROPSCIENCE AG (DE) | 2007-07-11 | — | — | CN | disclosed |
| CN-1578625-A | Substituted thiophen-3-yl-sulfonylamino carbonyl-triazolin (thi) ones | BAYER CROPSCIENCE AG (DE) | 2005-02-09 | — | — | CN | disclosed |
| US-20050014809-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
| EP-1443822-A1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer CropScience AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003037086-A1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014809-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones | DDT, TARS2, TST | KDM4E 403/4885TSHR 229/4885CA1 3788/4885 |
| US-20080269061-A1 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | DDT, NAT1, TARS2 | KDM4E 1152/4885TSHR 277/4885CA1 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.