Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222126 | 0.90 | ALDH1A1 (0.45) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL3219800 | 0.86 | TSHR (0.42) | TSHRKMT2AMEN1CA1CA2 | |
| SCHEMBL3211322 | 0.84 | CA12 (0.45) | TSHRKMT2AMEN1CA1CA2 | |
| SCHEMBL3215781 | 0.84 | MAPT (0.41) | TSHRKMT2ACA1CA2CA9 | |
| SCHEMBL27546956 | 0.84 | TSHR (0.40) | TSHRKMT2AMEN1CA1CA2 | |
| SCHEMBL3219726 | 0.84 | TSHR (0.40) | TSHRKMT2AMEN1CA1CA2 | |
| SCHEMBL3212013 | 0.82 | TSHR (0.42) | TSHRKMT2AMEN1CA1CA2 | |
| SCHEMBL4377938 | 0.81 | KDM4E (0.39) | TSHRKMT2AMEN1CA1CA2 | |
| SCHEMBL3218265 | 0.80 | CA12 (0.36) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL5891662 | 0.80 | KMT2A (0.39) | TSHRKMT2AMEN1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-6964939-B1 | Substituted thiene-3-yl-sulfonyl amino(thio)carbonyl-triazolin(thi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-15 | — | — | US | disclosed |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | disclosed |
| EP-1200426-B1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-1200426-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005788-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, CCNE2 | TSHR 613/4885KMT2A 1752/4885MEN1 727/4885 |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, SULT2A1 | TSHR 55/4885KMT2A 1327/4885MEN1 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.