Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.46 |
| ▸ | ARG2 | P78540 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811491 | 1.00 | ARG1 (0.46) | ARG1ARG2GRM2GABRA5GABRB2 | |
| SCHEMBL1846158 | 0.88 | ARG1 (0.41) | ARG1ARG2GRM2GABRA5GABRB2 | |
| SCHEMBL26777875 | 0.84 | — | — | |
| SCHEMBL5323379 | 0.84 | — | — | |
| SCHEMBL4513896 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL361546 | 0.82 | GRM2 (0.48) | GRM2TSHREPHX1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL361545 | 0.82 | GRM2 (0.48) | GRM2TSHREPHX1MEN1KMT2A | |
| SCHEMBL16107193 | 0.80 | GRM2 (0.47) | GRM2TSHREPHX1 | |
| SCHEMBL29956128 | 0.80 | GRM2 (0.47) | GRM2TSHREPHX1MEN1KMT2A | |
| SCHEMBL29956011 | 0.80 | GRM2 (0.47) | GRM2TSHREPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368432-B2 | Conotoxin peptides | XENOME, LTD. (AU) | 2008-05-06 | — | — | US | claimed |
| US-20080081901-A1 | ALPHA-CONOTOXIN PEPTIDES | THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2008-04-03 | — | — | US | claimed |
| US-7279549-B2 | Apha-conotoxin peptides | THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2007-10-09 | — | — | US | claimed |
| US-6797808-B1 | FOUND NATURALLY IN VENOM OF THE CONE SNAILS; HAVE SPECIFICITY FOR NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS; FOR TREATING CARDIOVASCULAR, GASTRIC MOTILITY, AND MOOD DISORDERS, URINARY INCONTINENCE, NICOTINE ADDICTION, AND SMALL CELL LUNG CANCER | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2004-09-28 | — | — | US | claimed |
| US-11022612-B2 | BARD1 isoforms in lung and colorectal cancer and use thereof | HOPITAUX UNIVERSITAIRES DE GENEVE (CH) | 2021-06-01 | — | — | US | disclosed |
| US-10865316-B2 | Conotoxin peptides for use in biofouling deterrence | CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) | 2020-12-15 | — | — | US | disclosed |
| EP-3298086-B1 | CONOTOXIN PEPTIDES FOR USE IN BIOFOULING DETERRENCE | UNIV CLEMSON RES FOUNDATION (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10730912-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD. (CH) | 2020-08-04 | — | — | US | disclosed |
| US-20200071544-A1 | Conotoxin Peptides for Use in Biofouling Deterrence | CLEMSON UNIVERSITY RESEARCH FOUNDATION | 2020-03-05 | — | — | US | disclosed |
| US-10562933-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | POLYPHOR LTD. (CH) | 2020-02-18 | — | — | US | disclosed |
| US-20190002498-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD (CH) | 2019-01-03 | — | — | US | disclosed |
| EP-2606358-B1 | BARD1 ISOFORMS IN LUNG AND COLORECTAL CANCER AND USE THEREOF | UNIV GENEVE (CH) | 2018-12-26 | — | — | EP | disclosed |
| WO-2002002590-A2 | I-SUPERFAMILY CONOTOXINS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-1147130-A1 | ALPHA-CONOTOXIN PEPTIDES | University of Utah Research Foundation (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2001049312-A2 | O-SUPERFAMILY CONOTOXIN PEPTIDES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2001-07-12 | — | — | WO | disclosed |
| WO-2001035985-A1 | P-SUPERFAMILY CONOPEPTIDES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001021648-A1 | USES OF KAPPA-CONOTOXIN PVIIA | COGNETIX, INC. (US) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001018033-A1 | GAMMA-CARBOXYGLUTAMATE CONTAINING CONOPEPTIDES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2001-03-15 | — | — | WO | disclosed |
| WO-2000076532-A1 | νO-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000044776-A1 | ALPHA-CONOTOXIN PEPTIDES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2000-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002498-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | CTSG, CTRL, PREP | ARG1 1178/4885ARG2 3759/4885GRM2 4700/4885 |
| US-10730912-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLL, POLM, POLR1C | ARG1 111/4885ARG2 759/4885GRM2 3840/4885 |
| US-10562933-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | CTSG, CTRL, PREP | ARG1 1178/4885ARG2 3759/4885GRM2 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.