Hydrochloric Acid

Hydrochloric Acid

SCHEMBL437861

CC1=Cc2ccccc2C1[Zr+2](=C(c1ccccc1)c1ccccc1)C1C(C)=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31024191 1.00 LMNA (0.39) LMNACES2CES1
Hydrochloric Acid SCHEMBL2868431 0.93 LMNA (0.35) LMNA
Hydrochloric Acid SCHEMBL439350 0.87 LMNA (0.34) LMNA
Hydrochloric Acid SCHEMBL2866783 0.87 LMNA (0.33) LMNA
Hydrochloric Acid SCHEMBL438830 0.86 LMNA (0.35) LMNACES2CES1
Hydrochloric Acid SCHEMBL31024197 0.86 LMNA (0.35) LMNACES2CES1
Hydrochloric Acid SCHEMBL7928101 0.83 LMNA (0.34) LMNA
Hydrochloric Acid SCHEMBL2861546 0.83 LMNA (0.32) LMNA
Hydrochloric Acid SCHEMBL2860865 0.83 LMNA (0.33) LMNA
Hydrochloric Acid SCHEMBL436801 0.81 ALDH1A1 (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871885-B2 Ethylene-a-olefin copolymer and molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-28 US disclosed
US-8501891-B2 Ethylene-α-olefin copolymer and molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-06 US disclosed
US-8299194-B2 Ethylene-α-olefin copolymer and article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-20120123006-A1 RESIN COMPOSITION FOR CROSSLINKING/FOAM MOLDING, CROSSLINKED MOLDED FOAM, MEMBER FOR FOOTWEAR, AND FOOTWEAR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-17 US disclosed
US-20120065351-A1 ETHYLENE-ALPHA-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-15 US disclosed
US-20120065352-A1 ETHYLENE-A-OLEFIN COPOLYMER AND ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-15 US disclosed
US-20110136994-A1 OLEFIN POLYMERIZATION CATALYST AND PRODUCTION PROCESS OF OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-09 US disclosed
US-20110040059-A1 ETHYLENE-a-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-17 US disclosed
US-20100310799-A1 ETHYLENE-a-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED 2010-12-09 US disclosed
US-20100305292-A1 ETHYLENE-a-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-02 US disclosed
US-6143827-A CONJUGATED DIENE COPOLYMER; MOLDABILITY, TENSILE STRENGTH MITSUI CHEMICALS INC (JP) 2000-11-07 US disclosed
US-6133490-A WAX OF COPOLYMER OF ETHYLENE WITH AN AROMATIC VINYL COMPOUND. MITSUI CHEMICALS INC. (JP) 2000-10-17 US disclosed
US-6015625-A COMPOSITION CONTAINING ALPHA-OLEFIN/AROMATIC VINYL COMPOUND RANDOM COPOLYMER GRAFT MODIFIED WITH UNSATURATED CARBOXYLIC ACID OR DERIVATIVE MITSUI CHEMICALS, INC. (JP) 2000-01-18 US disclosed
EP-0930329-A1 SHRINKABLE FILM MADE FROM OLEFIN COPOLYMER Mitsui Chemicals, Inc. (JP) 1999-07-21 EP disclosed
EP-0896983-A1 PIGMENT DISPERSANT FOR AROMATIC POLYMERS Mitsui Chemicals, Inc. (JP) 1999-02-17 EP disclosed
EP-0896044-A1 ADHESIVE RESIN COMPOSITION AND LAMINATE MADE USING THE SAME AS ADHESIVE LAYER Mitsui Chemicals, Inc. (JP) 1999-02-10 EP disclosed
EP-0893245-A1 VULCANIZED MOLDING HAVING SURFACE DECORATIVE LAYER, PAINTED THERMOPLASTIC RESIN COMPOSITION, AND PAINTED ELASTOMER COMPOSITION Mitsui Chemicals, Inc. (JP) 1999-01-27 EP disclosed
EP-0892013-A1 Unsaturated elastomer compositions and their vulcanized rubbers Mitsui Chemicals, Inc. (JP) 1999-01-20 EP disclosed
EP-0892014-A1 Olefin thermoplastic elastomer composition Mitsui Chemicals, Inc. (JP) 1999-01-20 EP disclosed
EP-0889091-A1 RUBBER COMPOSITIONS FOR TIRES Mitsui Chemicals, Inc. (JP) 1999-01-07 EP disclosed