Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 9/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5402357 | 0.86 | POLB (0.46) | POLBMAPK1HSD17B10MAOBMAOA | |
| SCHEMBL395587 | 0.78 | CHRM2 (0.33) | ELOVL1 | |
| SCHEMBL5399689 | 0.77 | POLB (0.39) | POLBMAPK1HSD17B10MAOBMAOA | |
| SCHEMBL395529 | 0.77 | MTNR1A (0.33) | ELOVL1 | |
| SCHEMBL5410828 | 0.76 | POLB (0.38) | POLBMAPK1HSD17B10MAOBMAOA | |
| SCHEMBL5415163 | 0.75 | MAOB (0.45) | MAPK1HSD17B10MAOBMAOAACHE | |
| SCHEMBL5413428 | 0.75 | L3MBTL1 (0.40) | MAOBMAOAACHEELOVL1GSTP1 | |
| SCHEMBL5407812 | 0.74 | POLB (0.36) | POLBMAPK1HSD17B10MAOBMAOA | |
| SCHEMBL5413487 | 0.74 | CHRM4 (0.37) | POLBMAPK1HSD17B10MAOBMAOA | |
| SCHEMBL5423439 | 0.74 | MEN1 (0.43) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088914-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-12 | — | — | US | disclosed |
| US-8101753-B2 | Production method of pyrimidine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| EP-1809610-B1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1809610-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006051891-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088914-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHODH | POLB 253/4885MAPK1 2739/4885HSD17B10 1445/4885 |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHODH | POLB 253/4885MAPK1 2739/4885HSD17B10 1445/4885 |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | ALK, DPYD, DDT | POLB 560/4885MAPK1 2333/4885HSD17B10 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.