Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.54 |
| ▸ | ITGAV | P06756 | 12/20 | 0.54 |
| ▸ | OGA | O60502 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372614 | 1.00 | ITGB3 (0.54) | ITGB3ITGAVOGAITGA2B | |
| SCHEMBL4374753 | 0.91 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL4379967 | 0.91 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL7187503 | 0.86 | ITGAV (0.48) | ITGB3ITGAVOGAITGA2B | |
| SCHEMBL7944308 | 0.80 | ITGB3 (0.82) | ITGB3ITGAVITGA2B | |
| SCHEMBL3889424 | 0.80 | ITGB3 (0.82) | ITGB3ITGAVITGA2B | |
| SCHEMBL4378963 | 0.80 | ITGB3 (0.82) | ITGB3ITGAVITGA2B | |
| SCHEMBL3889422 | 0.80 | ITGB3 (0.82) | ITGB3ITGAVITGA2B | |
| SCHEMBL7947722 | 0.80 | ITGB3 (0.55) | ITGB3ITGAVOGAITGA2B | |
| SCHEMBL7947726 | 0.80 | ITGB3 (0.55) | ITGB3ITGAVOGAITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | claimed |
| EP-1047425-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-11-02 | — | — | EP | claimed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | claimed |