SCHEMBL4379359

SCHEMBL4379359

CC1CCC(C(C)C)C(C(=O)OC(C)(C)C)C1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.58
TRPM8 Q7Z2W7 5/20 0.49
TRPA1 O75762 2/20 0.44
TRPV1 Q8NER1 6/20 0.41
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15268374 0.87 EPHX1 (0.41) EPHX1TRPM8TRPA1TRPV1
SCHEMBL30566245 0.82 EPHX1 (0.53) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL13043160 0.81 EPHX1 (0.64) EPHX1TRPM8TRPA1TRPV1
SCHEMBL21350183 0.81 EPHX1 (0.64) EPHX1TRPM8TRPA1TRPV1
SCHEMBL1439243 0.81 EPHX1 (0.64) EPHX1TRPM8TRPA1TRPV1
SCHEMBL1238085 0.80 EPHX1 (0.62) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL1439241 0.80 EPHX1 (0.62) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL6923690 0.80 EPHX1 (0.62) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL18786188 0.80 TRPM8 (0.55) EPHX1TRPM8TRPA1TRPV1
SCHEMBL2058006 0.79 TRPM8 (0.54) EPHX1TRPM8TRPA1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed
US-6372854-B1 POLYALKENAMERS USED AS PHOTORESISTS HAVING EXCELLENT OPTICAL ELECTRICAL PROPERTIES; HIGH RIGIDITY; HEAT RESISTANCE; ADHESION AND WEAR RESISTANCE; HYDROGENATION; ACIDOLYSIS MITSUI CHEMICALS, INC. (JP) 2002-04-16 US disclosed