Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.62 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1238085 | 1.00 | EPHX1 (0.62) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL2057748 | 0.85 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL6128506 | 0.85 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL12381600 | 0.85 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL10034576 | 0.85 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL291653 | 0.85 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL10001728 | 0.85 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL21350183 | 0.84 | EPHX1 (0.64) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL13043160 | 0.84 | EPHX1 (0.64) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL1439243 | 0.84 | EPHX1 (0.64) | EPHX1TRPM8TRPA1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112122-A1 | EPIMINOCYCLOALKYL[b] INDOLE DERIVATIVES AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS AND USES THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-05-12 | — | — | US | disclosed |
| WO-2011044134-A1 | EPIMINOCYCLOALKYL(B)INDOLE DERIVATIVES AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS AND USES THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112122-A1 | EPIMINOCYCLOALKYL[b] INDOLE DERIVATIVES AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS AND USES THEREOF | HTR6, HTR3B, HTR1B | EPHX1 208/4885TRPM8 3646/4885TRPA1 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.