Biotin

Biotin

SCHEMBL437943

Nc1ccc2ncccc2c1.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.61
▸ MEN1 O00255 1/20 0.61
▸ ABL1 P00519 1/20 0.61
▸ LMNA P02545 1/20 0.61
▸ PKM P14618 1/20 0.61
▸ IDE P14735 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ RIN1 Q13671 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ CA12 O43570 10/20 0.47
▸ CA1 P00915 10/20 0.47
▸ CA2 P00918 10/20 0.47
▸ CA9 Q16790 10/20 0.47
▸ HLCS P50747 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL5683818 0.83 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL18993019 0.81 TDP1 (0.83) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL28034601 0.81 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
SCHEMBL478407 0.81 TDP1 (0.53) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22800855 0.81 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL28516341 0.79 TDP1 (0.92) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL438197 0.79 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL11275953 0.79 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL16540693 0.79 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL19927391 0.78 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10793481-B2 Methods for treating a plant exposed to a phytotoxicant YAMASHITA THOMAS T (US) 2020-10-06 — — US disclosed
US-10683244-B2 Method for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2020-06-16 — — US disclosed
US-10683238-B2 Fertilizer compositions comprising a cellulose nutrient component and methods for using same YAMASHITA THOMAS T (US) 2020-06-16 — — US disclosed
US-10570067-B2 Compositions for enhancing pollination and methods for using same YAMASHITA THOMAS T (US) 2020-02-25 — — US disclosed
US-20190335750-A1 Method for Amelioration of the Glyphosate Effect LIDOCHEM INC (US) 2019-11-07 — — US disclosed
US-20190185388-A1 Fertilizer Compositions Comprising a Cellulose Nutrient Component and Methods for Using Same YAMASHITA THOMAS T (US) 2019-06-20 — — US disclosed
US-10189750-B2 Fertilizer compositions comprising a cellulose nutrient component and methods for using same YAMASHITA THOMAS T (US) 2019-01-29 — — US disclosed
US-20190023627-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2019-01-24 — — US disclosed
US-10172352-B1 Method for amelioration of the glyphosate effect LIDOCHEM, INC. (US) 2019-01-08 — — US disclosed
US-10106472-B2 Compositions for controlling plant parasitic nematodes and methods for using same YAMASHITA THOMAS T (US) 2018-10-23 — — US disclosed
EP-1094827-A1 PRION PROTEIN AND USES THEREOF V.I. Technologies, Inc. (US) 2001-05-02 — — EP disclosed
WO-2000002575-A1 PRION PROTEIN AND USES THEREOF V.I. TECHNOLOGIES, INC. (US) 2000-01-20 — — WO disclosed
US-5797976-A AQUEOUS NUTRIENT AS CROP GROWTH STIMULANTS YAMASHITA THOMAS T (US) 1998-08-25 — — US disclosed
EP-0544759-B1 DETOXIFICATION OF SOIL YAMASHITA THOMAS T (US) 1997-07-30 — — EP disclosed
US-5582627-A TREATMENT OF SOIL CONTAMINATED WITH HERBICIDES AND PESTICIDES COMPRISING ADDING NUTRIENT MEDIUM, COMPLEXING MEDIUM, NITROGEN AND PHOSPHORUS NUTRIENTS YAMASHITA THOMAS T (US) 1996-12-10 — — US disclosed
US-5549729-A CONSISTS OF CARBON SKELETON/ENERGY COMPONENT, MACRONUTRIENT COMPONENT AND VITAMIN/COFACTOR COMPONENT; SUITABLE FOR FOLIAR SPRAYS YAMASHITA THOMAS T (US) 1996-08-27 — — US disclosed
EP-0433394-B1 METHOD OF APPLYING ENERGY, CARBON SKELETON AND NUTRIENT MATERIALSTO VEGETATION YAMASHITA THOMAS T (US) 1995-11-08 — — EP disclosed
EP-0544759-A4 DETOXIFICATION OF SOIL YAMASHITA THOMAS T (US) 1994-06-01 — — EP disclosed
EP-0544759-A1 DETOXIFICATION OF SOIL. YAMASHITA THOMAS T (US) 1993-06-09 — — EP disclosed
WO-1992003393-A1 DETOXIFICATION OF SOIL YAMASHITA THOMAS T (US) 1992-03-05 — — WO disclosed
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