Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | IDE | P14735 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | CA12 | O43570 | 8/20 | 0.54 |
| ▸ | CA1 | P00915 | 8/20 | 0.54 |
| ▸ | CA2 | P00918 | 8/20 | 0.54 |
| ▸ | CA9 | Q16790 | 8/20 | 0.54 |
| ▸ | HLCS | P50747 | 3/20 | 0.51 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biotin SCHEMBL22800855 | 0.95 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL18993019 | 0.90 | TDP1 (0.83) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL4350764 | 0.88 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL16540693 | 0.85 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL23124079 | 0.85 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL723192 | 0.84 | TDP1 (0.90) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL21981206 | 0.84 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL22943835 | 0.84 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL20547409 | 0.84 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL38817 | 0.84 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399683-A1 | Composition and Methods For Affinity Directed Enrichment of Rare Species | SPARK MOLECULAR DIAGNOSTICS, INC. | 2020-12-24 | — | — | US | disclosed |
| EP-3746567-A1 | COMPOSITION AND METHODS FOR AFFINITY DIRECTED ENRICHMENT OF RARE SPECIES | CY Molecular Diagnostics, Inc (US) | 2020-12-09 | — | — | EP | disclosed |
| WO-2019165469-A1 | COMPOSITION AND METHODS FOR AFFINITY DIRECTED ENRICHMENT OF RARE SPECIES | CY MOLECULAR DIAGNOSTICS, INC (US) | 2019-08-29 | — | — | WO | disclosed |
| EP-1192467-B1 | CHEMILUMINESCENCE REDOX ASSAY TO QUANTIFY ANALYTES IN BIOLOGICAL SAMPLES | ABBOTT LAB (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2003104424-A2 | NOVEL MOLECULAR CONJUGATES FOR SIGNAL AMPLIFICATION | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-12-18 | — | — | WO | disclosed |
| EP-1192467-A1 | CHEMILUMINESCENCE REDOX ASSAY TO QUANTIFY ANALYTES IN BIOLOGICAL SAMPLES | ABBOTT LABORATORIES (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000079282-A1 | CHEMILUMINESCENCE REDOX ASSAY TO QUANTIFY ANALYTES IN BIOLOGICAL SAMPLES | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | disclosed |
| US-6127140-A | Assay for quantitative measurement of analytes in biological samples | ABBOTT LABORATORIES (US) | 2000-10-03 | — | — | US | disclosed |