Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836929 | 1.00 | NAMPT (0.46) | NAMPTLMNAADRB2ADRB1ADRB3 | |
| SCHEMBL2836312 | 0.94 | NAMPT (0.44) | NAMPTLMNAADRB2ADRB1ADRB3 | |
| SCHEMBL2836318 | 0.93 | NAMPT (0.47) | NAMPTLMNAADRB2ADRB1ADRB3 | |
| SCHEMBL2836523 | 0.92 | ADRB2 (0.44) | NAMPTLMNAADRB2ADRB1ADRB3 | |
| SCHEMBL2833174 | 0.92 | NAMPT (0.52) | NAMPTITGB3ITGAV | |
| SCHEMBL2833009 | 0.92 | HPSE (0.42) | NAMPTMEN1KMT2AITGB3ITGAV | |
| SCHEMBL2836494 | 0.87 | ITGB3 (0.49) | NAMPTADRB2ADRB1ADRB3ITGB3 | |
| SCHEMBL2841321 | 0.86 | TSHR (0.51) | NAMPTLMNAADRB2ADRB1ADRB3 | |
| SCHEMBL2838519 | 0.86 | LMNA (0.43) | LMNAALDH1A1MAPTKMT2AITGB3 | |
| SCHEMBL2832015 | 0.86 | NAMPT (0.47) | NAMPTLMNAADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061448-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |