Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387581 | 0.83 | RAB9A (0.63) | HPGDRAB9ALMNASMN1; SMN2NPC1 | |
| Oxalic Acid SCHEMBL7994699 | 0.82 | CHEK1 (0.37) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| Oxalic Acid SCHEMBL8934783 | 0.81 | MAPT (0.34) | HPGDRAB9ALMNASMN1; SMN2NPC1 | |
| Oxalic Acid SCHEMBL7991119 | 0.81 | SMN1; SMN2 (0.40) | HPGDRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL4391835 | 0.79 | GRM4 (0.37) | RAB9ASMN1; SMN2NPC1MAPT | |
| Oxalic Acid SCHEMBL7990904 | 0.78 | RXFP1 (0.43) | HPGDRAB9ALMNAGAAALDH1A1 | |
| SCHEMBL4379687 | 0.78 | KMT2A (0.50) | RAB9ASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8367864 | 0.78 | FNTA (0.49) | SMN1; SMN2ALDH1A1MAPK1NPSR1 | |
| SCHEMBL4543312 | 0.77 | KMT2A (0.49) | ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8366423 | 0.77 | FNTA (0.48) | SMN1; SMN2ALDH1A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |