Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8934827 | 0.90 | POLB (0.35) | ALDH1A1LMNAKMT2ARAB9AHPGD | |
| Oxalic Acid SCHEMBL8934852 | 0.90 | POLB (0.35) | ALDH1A1LMNAKMT2ARAB9AHPGD | |
| Oxalic Acid SCHEMBL7991119 | 0.86 | SMN1; SMN2 (0.40) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 | |
| Oxalic Acid SCHEMBL7988233 | 0.84 | HRH3 (0.41) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| Oxalic Acid SCHEMBL7977323 | 0.82 | HRH3 (0.43) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL4379745 | 0.81 | HPGD (0.43) | MAPTALDH1A1LMNAMEN1HTT | |
| SCHEMBL4379711 | 0.81 | HRH3 (0.43) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| Oxalic Acid SCHEMBL8795914 | 0.81 | MAOB (0.35) | MAPTALDH1A1LMNAMEN1HTT | |
| Oxalic Acid SCHEMBL8795918 | 0.81 | MAOB (0.35) | MAPTALDH1A1LMNAMEN1HTT | |
| SCHEMBL4391835 | 0.80 | GRM4 (0.37) | MAPTRAB9ASMN1; SMN2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |