SCHEMBL4380113

SCHEMBL4380113

C=CS(=O)(=O)c1cc(OC)c(N)cc1OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.39
S100B P04271 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
F2 P00734 2/20 0.36
PRSS1 P07477 2/20 0.36
PRSS2 P07478 2/20 0.36
PRSS3 P35030 2/20 0.36
ALDH1A1 P00352 5/20 0.36
CYP3A4 P08684 3/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10785254 0.93 PKM (0.54) PKML3MBTL1POLBGAAS100B
SCHEMBL11025630 0.87 PKM (0.47) PKML3MBTL1POLBGAAALDH1A1
SCHEMBL7718749 0.87 PKM (0.51) PKML3MBTL1POLBGAAS100B
SCHEMBL4394640 0.85 GAA (0.51) PKML3MBTL1POLBGAAS100B
SCHEMBL11671249 0.83 PKM (0.44) PKML3MBTL1POLBGAAALDH1A1
SCHEMBL4650366 0.80 PKM (0.70) PKML3MBTL1POLBGAAS100B
SCHEMBL10346964 0.79 PKM (0.39) PKMGAAALDH1A1TSHRKDM4E
SCHEMBL30068292 0.78 PKM (1.00) PKML3MBTL1POLBGAAS100B
SCHEMBL8777777 0.78 PKM (1.00) PKML3MBTL1POLBGAAS100B
SCHEMBL7717678 0.78 ALDH1A1 (0.44) PKML3MBTL1POLBGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010069726-A2 DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2010-06-24 WO disclosed
EP-1411090-B1 Monoazo reactive red dyestuff EVERLIGHT USA INC (US) 2009-11-25 EP disclosed
US-6815536-B2 DYESTUFFS FOR DYEING AND PRINTING OF MATERIALS CONTAINING EITHER CELLULOSE FIBERS, SUCH AS COTTON, ARTIFICIAL COTTON, LINEN, AND ARTIFICIAL LINEN, OR SYNTHETIC POLYAMIDE, SUCH AS WOOL, SILK, AND NYLON ETC. EVERLIGHT USA, INC. 2004-11-09 US disclosed
US-20040087780-A1 Monoazo reactive red dyestuff EVERLIGHT USA, INC. 2004-05-06 US disclosed
EP-1411090-A1 Monoazo reactive red dyestuff Everlight USA, Inc. (US) 2004-04-21 EP disclosed
EP-0777703-B1 DICYCLIC METAL COMPLEX FORMAZAN DERIVATIVES, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME AND DYEING PROCESS EMPLOYING THE SAME KYUNGIN SYNTHETIC CORP (KR) 2003-06-25 EP disclosed
US-6407220-B1 FOR DYEING AND PRINTING OF MATERIALS CONTAINING CELLULOSE FIBERS; HIGH FIXATION AND GOOD BUILD-UP EVERLIGHT USA, INC. 2002-06-18 US disclosed
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
EP-0652262-B1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 2000-07-12 EP disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
EP-0133843-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-03-06 EP disclosed
EP-0056975-B1 WATER SOLUBLE MONOAZOCOMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-16 EP disclosed
EP-0128340-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
EP-0122599-A1 Fiber-reactive yellow azo dyestuffs AMERICAN HOECHST CORPORATION (US) 1984-10-24 EP disclosed
EP-0040806-B1 WATER-SOLUBLE, COLOURED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-19 EP disclosed
EP-0042108-B1 REACTIVE DYES, THEIR USE AND CELLULOSE FIBERS DYED THEREWITH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-04 EP disclosed
EP-0099721-A1 Reactive metal formazan blue dye SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-02-01 EP disclosed
EP-0056975-A2 Water soluble monoazocompounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1982-08-04 EP disclosed
EP-0042108-A1 Reactive dyes, their use and cellulose fibers dyed therewith SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-23 EP disclosed
EP-0040806-A2 Water-soluble, coloured compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-02 EP disclosed