SCHEMBL4650366

SCHEMBL4650366

COc1cc(S(=O)(=O)O)c(OC)cc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.70
ALDH1A1 P00352 4/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP13 P45452 1/20 0.44
GAA P10253 2/20 0.42
F2 P00734 3/20 0.42
PRSS1 P07477 3/20 0.42
PRSS2 P07478 3/20 0.42
PRSS3 P35030 3/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649818 0.92 PKM (0.59) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL1755131 0.89 PKM (0.55) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL4649757 0.89 PKM (0.59) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL8113725 0.89 PKM (0.59) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL8568415 0.89 PKM (0.55) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL1888725 0.88 ALDH1A1 (0.51) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL2914715 0.86 PKM (0.56) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL9753036 0.86 PKM (0.54) PKMALDH1A1LMNAMAPTKMT2A
SCHEMBL153566 0.85 PKM (0.56) PKMALDH1A1LMNAKMT2AL3MBTL1
SCHEMBL9233010 0.85 PKM (0.51) PKMALDH1A1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697467-B1 TRISAZO-DYESTUFFS FUJIFILM IMAGING COLORANTS LTD (GB) 2012-12-26 EP disclosed
US-7638609-B2 Trisazo-dyestuffs FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-12-29 US disclosed
US-7638609-B2 Trisazo-dyestuffs FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-12-29 US disclosed
EP-1000123-B1 USE OF REACTIVE DYES FOR DYEING HAIR BASF SE (DE) 2008-09-10 EP disclosed
CN-100395292-C Water-soluble reactive mono- and di-azo dyes DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-06-18 CN disclosed
US-20070062409-A1 Trisazo-dyestuffs FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-03-22 US disclosed
US-20070062409-A1 Trisazo-dyestuffs FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-03-22 US disclosed
US-7109313-B2 Water-soluble reactive mono- and di-azo dyes DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2006-09-19 US disclosed
EP-1490440-B1 WATER-SOLUBLE REACTIVE MONO- AND DI-AZO DYES DYSTAR TEXTILFARBEN GMBH & CO (DE) 2006-08-23 EP disclosed
CN-1643078-A Water-soluble reactive mono- and di-azo dyes DYSTAR TEXTILFARBEN GMBH & CO (DE) 2005-07-20 CN disclosed
EP-0033852-A1 Water-soluble disazo dyestuffs, their preparation and use CASSELLA Aktiengesellschaft (DE) 1981-08-19 EP disclosed
EP-0012980-A1 Process for the preparation of 2,5-dialkoxy-aniline-4-sulfonic acids HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed
EP-0012969-A2 Water-soluble fibre-reactive compounds and their use in fibre finishing,especially as dyestuffs,and dihalogeno-pyridazonyl-carboxylic and sulfonic acid halides and their use as fibre-reactive anchors,as well as process for the preparation of these compound HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed
US-4125368-A Metallized monoazo dyes TOMS RIVER CHEMICAL CORP. (US) 1978-11-14 US disclosed
US-4124581-A FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed
US-4060521-A POLYAMIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed
US-4058515-A Metallized phenyl-azo-naphthol compounds TOMS RIVER CHEMICAL CORPORATION (US) 1977-11-15 US disclosed
US-4035350-A Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-3957751-A WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed