Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GGT1 | P19440 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667204 | 0.97 | HSD17B10 (0.65) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL3731927 | 0.94 | KDM4E (0.70) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL1868204 | 0.87 | KDM4E (0.63) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| Citric Acid SCHEMBL28178703 | 0.85 | KDM4E (0.48) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL7606600 | 0.84 | HSD17B10 (0.59) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL2780216 | 0.84 | HSD17B10 (0.59) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL11019069 | 0.84 | HSD17B10 (0.59) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL1821600 | 0.84 | HSD17B10 (0.59) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL2677485 | 0.84 | HSD17B10 (0.56) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL13725644 | 0.84 | PTGS2 (0.53) | HSD17B10KDM4ELMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191846-A | High-penetration composition and its application | 于崇曦 | 2018-06-22 | — | — | CN | disclosed |
| CN-107320732-A | High-penetration composition and its application | 于崇曦 | 2017-11-07 | — | — | CN | disclosed |
| CN-107261149-A | High-penetration composition and its application | 于崇曦 | 2017-10-20 | — | — | CN | disclosed |
| EP-2038251-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF ASPIRIN | Techfields Biochem Co. Ltd (CN) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008007171-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF ASPIRIN | TECHFIELDS BIOCHEM CO. LTD (CN) | 2008-01-17 | — | — | WO | disclosed |