SCHEMBL438047

SCHEMBL438047

CC(C)C(NN)C(=O)Nc1cccc(C(N)=O)c1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.65
PARP1 P09874 12/20 0.54
PARP10 Q53GL7 10/20 0.54
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
PARP14 Q460N5 4/20 0.51
PARP15 Q460N3 5/20 0.49
ALDH1A1 P00352 1/20 0.48
ADAMTS4 O75173 1/20 0.45
ROCK2 O75116 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30668647 0.83 PARP1 (0.60) POLBPARP1PARP10MEN1KMT2A
SCHEMBL12545738 0.83 PARP1 (0.60) POLBPARP1PARP10MEN1KMT2A
SCHEMBL17512438 0.81 PARP1 (0.58) POLBPARP1PARP10MEN1KMT2A
SCHEMBL29761319 0.75 PARP1 (0.63) PARP1PARP10MEN1KMT2APARP14
SCHEMBL895009 0.75 PARP1 (0.63) PARP1PARP10MEN1KMT2APARP14
SCHEMBL2850002 0.74 MEN1 (0.67) PARP1PARP10MEN1KMT2APARP14
SCHEMBL8256095 0.74 PARP1 (0.57) POLBPARP1PARP10MEN1KMT2A
SCHEMBL3652606 0.74 MEN1 (0.66) PARP1PARP10MEN1KMT2APARP14
SCHEMBL13841107 0.73 PARP1 (0.54) PARP1PARP10MEN1KMT2APARP14
Valine SCHEMBL9877455 0.73 PARP1 (0.53) POLBPARP1PARP10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9381174-B2 Composition and method for exterminating animal parasite MITSUI CHEMICALS AGRO, INC. (JP) 2016-07-05 US claimed
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE MITSUI CHEMICALS AGRO, INC. (JP) 2015-10-22 US claimed
EP-2915530-A1 COMPOSITION FOR ANIMAL PARASITE EXTERMINATION AND METHOD FOR ANIMAL PARASITE EXTERMINATION Mitsui Chemicals Agro, Inc. (JP) 2015-09-09 EP claimed
EP-2394986-B1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2013-12-04 EP claimed
US-8541473-B2 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient AGRO-KANESHO CO., LTD. (JP) 2013-09-24 US claimed
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2012-01-26 US claimed
EP-2394986-A1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2011-12-14 EP claimed
US-9381174-B2 Composition and method for exterminating animal parasite MITSUI CHEMICALS AGRO, INC. (JP) 2016-07-05 US disclosed
US-9381174-B2 Composition and method for exterminating animal parasite MITSUI CHEMICALS AGRO, INC. (JP) 2016-07-05 US disclosed
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE MITSUI CHEMICALS AGRO, INC. (JP) 2015-10-22 US disclosed
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE MITSUI CHEMICALS AGRO, INC. (JP) 2015-10-22 US disclosed
EP-2915530-A1 COMPOSITION FOR ANIMAL PARASITE EXTERMINATION AND METHOD FOR ANIMAL PARASITE EXTERMINATION Mitsui Chemicals Agro, Inc. (JP) 2015-09-09 EP disclosed
EP-2915530-A1 COMPOSITION FOR ANIMAL PARASITE EXTERMINATION AND METHOD FOR ANIMAL PARASITE EXTERMINATION Mitsui Chemicals Agro, Inc. (JP) 2015-09-09 EP disclosed
US-8541473-B2 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient AGRO-KANESHO CO., LTD. (JP) 2013-09-24 US disclosed
US-8541473-B2 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient AGRO-KANESHO CO., LTD. (JP) 2013-09-24 US disclosed
CN-102378754-A 3-aminoxalylaminobenzamide derivatives, and insecticidal and miticidal agents containing same as active ingredient AGRO KANESHO CO LTD 2012-03-14 CN disclosed
CN-102378754-A 3-aminoxalylaminobenzamide derivatives, and insecticidal and miticidal agents containing same as active ingredient AGRO KANESHO CO LTD 2012-03-14 CN disclosed
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2012-01-26 US disclosed
EP-2394986-A1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2011-12-14 EP disclosed
WO-2010090282-A1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT アグロカネショウ株式会社 (JP) 2010-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT HDHD5, CBR3, BAK1 POLB 3622/4885PARP1 2095/4885PARP10 1264/4885
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE HDHD5, H1-3, TUBA3C POLB 1444/4885PARP1 4472/4885PARP10 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.