Apaflurane

Apaflurane

SCHEMBL4380845

FC(C(F)(F)F)C(F)(F)F.OC(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Apaflurane SCHEMBL19860 0.78 ALDH1A1 (0.33)
SCHEMBL25616 0.78
SCHEMBL29261476 0.73
SCHEMBL31548817 0.73
Apaflurane SCHEMBL27772978 0.73 ALDH1A1 (0.31)
Apaflurane SCHEMBL7649343 0.73 ALDH1A1 (0.31)
Apaflurane SCHEMBL17867718 0.73 ALDH1A1 (0.31)
SCHEMBL9478013 0.73
Perflutren SCHEMBL9417226 0.72 LMNA (0.30)
SCHEMBL20917 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2063073-A2 Working fluids for thermal energy conversion of waste heat form fuel cells using rankine cycle systems Honeywell International Inc. (US) 2009-05-27 EP claimed
US-7428816-B2 Working fluids for thermal energy conversion of waste heat from fuel cells using Rankine cycle systems HONEYWELL INTERNATIONAL INC. (US) 2008-09-30 US claimed
JP-2008506819-A 2008-03-06 JP claimed
EP-1773962-A2 WORKING FLUIDS FOR THERMAL ENERGY CONVERSION OF WASTE HEAT FROM FUEL CELLS USING RANKINE CYCLE SYSTEMS Honeywell International Inc. (US) 2007-04-18 EP claimed
WO-2006014609-A2 WORKING FLUIDS FOR THERMAL ENERGY CONVERSION OF WASTE HEAT FROM FUEL CELLS USING RANKINE CYCLE SYSTEMS HONEYWELL INTERNATIONAL, INC. (US) 2006-02-09 WO claimed
US-20060010872-A1 Working fluids for thermal energy conversion of waste heat from fuel cells using rankine cycle systems HONEYWELL INTERNATIONAL INC. 2006-01-19 US claimed
EP-2063073-A3 Working fluids for thermal energy conversion of waste heat form fuel cells using rankine cycle systems Honeywell International Inc. (US) 2013-12-18 EP disclosed
EP-2063073-A2 Working fluids for thermal energy conversion of waste heat form fuel cells using rankine cycle systems Honeywell International Inc. (US) 2009-05-27 EP disclosed
EP-2063073-A2 Working fluids for thermal energy conversion of waste heat form fuel cells using rankine cycle systems Honeywell International Inc. (US) 2009-05-27 EP disclosed
US-7428816-B2 Working fluids for thermal energy conversion of waste heat from fuel cells using Rankine cycle systems HONEYWELL INTERNATIONAL INC. (US) 2008-09-30 US disclosed
EP-1773962-A2 WORKING FLUIDS FOR THERMAL ENERGY CONVERSION OF WASTE HEAT FROM FUEL CELLS USING RANKINE CYCLE SYSTEMS Honeywell International Inc. (US) 2007-04-18 EP disclosed
WO-2006014609-A2 WORKING FLUIDS FOR THERMAL ENERGY CONVERSION OF WASTE HEAT FROM FUEL CELLS USING RANKINE CYCLE SYSTEMS HONEYWELL INTERNATIONAL, INC. (US) 2006-02-09 WO disclosed
US-20060010872-A1 Working fluids for thermal energy conversion of waste heat from fuel cells using rankine cycle systems HONEYWELL INTERNATIONAL INC. 2006-01-19 US disclosed