Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369373 | 0.98 | CYP2D6 (0.32) | KDM4ENPC1CYP1A2CYP2D6HPGD | |
| Hydrochloric Acid SCHEMBL2906352 | 0.98 | KDM4E (0.35) | KDM4ENPC1CYP1A2CYP2D6HPGD | |
| SCHEMBL588856 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL2904179 | 0.91 | KDM4E (0.40) | KDM4ENPC1CYP1A2CYP2D6HPGD | |
| SCHEMBL1547510 | 0.80 | CYP2D6 (0.34) | KDM4ENPC1CYP1A2CYP2D6HPGD | |
| SCHEMBL10326679 | 0.80 | CYP2D6 (0.34) | KDM4ENPC1CYP1A2CYP2D6HPGD | |
| SCHEMBL3229383 | 0.80 | CYP2D6 (0.34) | KDM4ENPC1CYP1A2CYP2D6HPGD | |
| SCHEMBL27817246 | 0.79 | SLC6A2 (0.31) | — | |
| SCHEMBL24922624 | 0.78 | CYP2D6 (0.33) | KDM4ENPC1CYP1A2CYP2D6HPGD | |
| SCHEMBL797872 | 0.78 | CYP2D6 (0.33) | KDM4ENPC1CYP1A2CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000126-B1 | HAIR DYEING COMPOSITION | KAO CORP (JP) | 2015-08-19 | — | — | EP | disclosed |
| US-8212037-B2 | Process for production of optically active quinuclidinols | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2012-07-03 | — | — | US | disclosed |
| US-7736396-B2 | mixing the first part containing an oxidative dye intermediate and second part containing hydrogen peroxide oxidizer immediately before use, applying mixture to the hair, leaving the hair for 1 to 60 minutes, then rinsing; 3-pyrrolidinyl-1,2,2-triethylpiperidine gives less damage to the hair; bleaching | KAO CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-7736396-B2 | mixing the first part containing an oxidative dye intermediate and second part containing hydrogen peroxide oxidizer immediately before use, applying mixture to the hair, leaving the hair for 1 to 60 minutes, then rinsing; 3-pyrrolidinyl-1,2,2-triethylpiperidine gives less damage to the hair; bleaching | KAO CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20090265864-A1 | mixing the first part containing an oxidative dye intermediate and second part containing hydrogen peroxide oxidizer immediately before use, applying mixture to the hair, leaving the hair for 1 to 60 minutes, then rinsing; 3-pyrrolidinyl-1,2,2-triethylpiperidine gives less damage to the hair; bleaching | KAO CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20090265864-A1 | mixing the first part containing an oxidative dye intermediate and second part containing hydrogen peroxide oxidizer immediately before use, applying mixture to the hair, leaving the hair for 1 to 60 minutes, then rinsing; 3-pyrrolidinyl-1,2,2-triethylpiperidine gives less damage to the hair; bleaching | KAO CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20090216019-A1 | Process for Production of Optically Active Quinuclidinols | KANTO KAGAKU KABUSHIKI KAISHA | 2009-08-27 | — | — | US | disclosed |
| EP-2000126-A1 | HAIR DYEING COMPOSITION | Kao Corporation (JP) | 2008-12-10 | — | — | EP | disclosed |
| EP-1867654-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE QUINUCLIDINOL | Nagoya Industrial Science Research Institute (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-6407103-B2 | POTENT ENZYME INHIBITORS OF CYCLIN-DEPENDENT KINASES RELATING TO THE CATALYTIC SUBUNITS CDK1-9 AND THEIR REGULATORY SUBUNITS CYCLINS A-H; ANTIPROLIFERATIVE, -CARCINOGENIC AND -TUMOR AGENTS; VIRICIDES; MODULATORS OF DNA/RNA BIOSYNTHESIS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-06-18 | — | — | US | disclosed |
| US-20010027195-A1 | Indeno [1,2-c]pyrazol-4-ones and their uses | DUPONT PHARMACEUTICALS COMPANY | 2001-10-04 | — | — | US | disclosed |
| US-3980788-A | XANTHENYL COMPOUNDS | SMITHKLINE CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010027195-A1 | Indeno [1,2-c]pyrazol-4-ones and their uses | CDK1, CCNA1, CDK19 | KDM4E 1717/4885NPC1 3502/4885CYP1A2 1796/4885 |
| US-20090216019-A1 | Process for Production of Optically Active Quinuclidinols | NQO2, ADH7, MRPL21 | KDM4E 1614/4885NPC1 4318/4885CYP1A2 111/4885 |
| US-20090265864-A1 | mixing the first part containing an oxidative dye intermediate and second part containing hydrogen peroxide oxidizer immediately before use, applying mixture to the hair, leaving the hair for 1 to 60 minutes, then rinsing; 3-pyrrolidinyl-1,2,2-triethylpiperidine gives less damage to the hair; bleaching | GPX4, GPX1, POLR1C | KDM4E 1899/4885NPC1 4417/4885CYP1A2 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.