Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | LGMN | Q99538 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802793 | 0.94 | CA12 (0.47) | CA12CA1CA2CA7CA13 | |
| SCHEMBL240017 | 0.83 | CA12 (0.44) | CA12CA1CA2CA7CA13 | |
| SCHEMBL4387010 | 0.82 | MAOA (0.46) | CA12CA1CA2CA7CA13 | |
| SCHEMBL3922530 | 0.78 | ALDH1A1 (0.50) | LGMNALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL4377762 | 0.76 | MAPT (0.59) | ALDH1A1KDM4ELMNAMAPTCYP1A2 | |
| SCHEMBL1354385 | 0.74 | MAOA (0.50) | CA12CA1CA2CA7CA13 | |
| SCHEMBL29173633 | 0.73 | CA12 (0.47) | CA12CA1CA2CA7CA13 | |
| Hydrochloric Acid SCHEMBL2385610 | 0.73 | MAOA (0.49) | CA12CA1CA2CA7CA13 | |
| SCHEMBL13634014 | 0.71 | MAOA (0.68) | CA12CA1CA2CA7CA13 | |
| SCHEMBL4387016 | 0.71 | MAOA (0.68) | CA12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899331-B1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-1899331-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000644-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-04 | — | — | WO | disclosed |