Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354385 | 0.93 | MAOA (0.50) | MAOAPDE3BPDE3AMAPTPIK3CA | |
| Hydrochloric Acid SCHEMBL2385610 | 0.91 | MAOA (0.49) | MAOAPDE3BPDE3AMAPTPIK3CA | |
| SCHEMBL4380979 | 0.82 | CA12 (0.43) | MAOAPDE3BPDE3AMAPTPIK3CA | |
| SCHEMBL15637920 | 0.81 | MAOA (0.45) | MAOAPDE3BPDE3AMAPTPIK3CA | |
| SCHEMBL238377 | 0.81 | ALDH1A1 (0.43) | MAPTGAASMN1; SMN2CA12CA1 | |
| Tetrahydrofuran SCHEMBL6653299 | 0.80 | MAOA (0.39) | MAOAPDE3BPDE3AMAPTPIK3CA | |
| Tetrahydrofuran SCHEMBL6653304 | 0.80 | MAOA (0.41) | MAOAPDE3BPDE3AMAPTALDH1A1 | |
| SCHEMBL4381301 | 0.79 | MAPT (0.59) | PDE3BPDE3AMAPTPIK3CAPIK3CB | |
| SCHEMBL5131921 | 0.77 | LGMN (0.47) | MAPTPIK3CAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4383340 | 0.76 | MAPT (0.52) | PDE3BPDE3AMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899331-B1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-1899331-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000644-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-04 | — | — | WO | disclosed |