⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14580329 | 0.79 | — | — | |
| SCHEMBL12724275 | 0.77 | CDK1 (0.47) | — | |
| SCHEMBL17040215 | 0.74 | — | — | |
| SCHEMBL506099 | 0.74 | DNMT1 (0.39) | — | |
| SCHEMBL1666675 | 0.73 | — | — | |
| SCHEMBL12451367 | 0.72 | CDK1 (0.47) | — | |
| SCHEMBL12702629 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL5694084 | 0.71 | DNMT1 (0.37) | — | |
| SCHEMBL25065522 | 0.70 | ADORA2A (0.36) | — | |
| SCHEMBL24248823 | 0.70 | GDA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023178133-A9 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023178133-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2022219636-A1 | ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS, AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-10-20 | — | — | WO | disclosed |
| US-20220298185-A1 | Nucleoside Prodrugs and Uses Related Thereto | UNIV EMORY (US) | 2022-09-22 | — | — | US | disclosed |
| EP-2970358-B1 | 3'-DEOXY NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2021-06-30 | — | — | EP | disclosed |
| EP-2970359-B1 | FLUORINATED PYRIMIDINE ANALOGS AND METHODS OF USE THEREOF | EPIGENETICS PHARMA LLC (US) | 2021-04-07 | — | — | EP | disclosed |
| WO-2021034373-A1 | CONJUGATES OF GUIDE RNA-CAS PROTEIN COMPLEX | ZHONG MINGHONG (US) | 2021-02-25 | — | — | WO | disclosed |
| US-20210054371-A1 | Conjugates of Guide RNA-Cas Protein Complex | ZHONG MINGHONG (US) | 2021-02-25 | — | — | US | disclosed |
| US-20100056771-A1 | Process of Making 2-Deoxy-2,2-Difluoro-D-Ribofuranosyl Nucleosides and Intermediates Therefor | SCINOPHARM TAIWAN LTD. (TW) | 2010-03-04 | — | — | US | disclosed |
| US-20100016252-A1 | Mannich Base N-Oxide Drugs | State of Oregon Acting By and Through The Oregon State Board of Higher Education On Behalf of The U (US) | 2010-01-21 | — | — | US | disclosed |
| US-7598246-B2 | Bisphosphonate conjugates and methods of making and using the same | MBC PHARMA, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598246-B2 | Bisphosphonate conjugates and methods of making and using the same | MBC PHARMA, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-20080293651-A1 | CYTOSINE NUCLEOSIDE ANALOGS AND ISOFLAVONES AND USES THEREOF | INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) | 2008-11-27 | — | — | US | disclosed |
| WO-2008118852-A1 | METHOD FOR TREATING AND PREVENTING ARTHRITIS | SOUTHERN RESEARCH INSTITUTE (US) | 2008-10-02 | — | — | WO | disclosed |
| US-20080139566-A1 | SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF | HOWELL AMY R | 2008-06-12 | — | — | US | disclosed |
| US-20080139566-A1 | SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF | HOWELL AMY R | 2008-06-12 | — | — | US | disclosed |
| US-7351827-B2 | Substituted oxetanes, method of making, and method of use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351827-B2 | Substituted oxetanes, method of making, and method of use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-01 | — | — | US | disclosed |