Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.83 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44658 | 0.91 | ESR1 (1.00) | ESR1ESR2TDP1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL11317436 | 0.89 | ESR1 (0.95) | ESR1ESR2TDP1TSHRLMNA | |
| SCHEMBL4373477 | 0.86 | TSHR (0.59) | ESR1ESR2TDP1TSHRLMNA | |
| SCHEMBL11551568 | 0.80 | ESR1 (0.64) | ESR1ESR2TDP1TSHRLMNA | |
| SCHEMBL9449569 | 0.80 | ESR1 (0.82) | ESR1ESR2TDP1LMNAIDO1 | |
| SCHEMBL30288156 | 0.78 | ESR1 (0.52) | ESR1ESR2TDP1LMNAIDO1 | |
| SCHEMBL28327538 | 0.77 | ESR1 (0.50) | ESR1ESR2TDP1TSHRLMNA | |
| SCHEMBL28598390 | 0.77 | ESR1 (0.50) | ESR1ESR2TDP1LMNAIDO1 | |
| SCHEMBL11869306 | 0.77 | TSHR (0.59) | ESR1ESR2TDP1TSHRLMNA | |
| SCHEMBL15263150 | 0.76 | MAPK1 (0.81) | ESR1ESR2TDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625988-B2 | Maintain flexibility | WILLIAM MARSH RICE UNIVERSITY (US) | 2009-12-01 | — | — | US | disclosed |
| US-7625988-B2 | Maintain flexibility | WILLIAM MARSH RICE UNIVERSITY (US) | 2009-12-01 | — | — | US | disclosed |
| US-20060178462-A1 | Flame retardant polymers | WILLIAM MARSH RICE UNIVERSITY (US) | 2006-08-10 | — | — | US | disclosed |
| WO-2004113265-A1 | FLAME RETARDANT POLYMERS | WILLIAM MARSH RICE UNIVERSITY (US) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178462-A1 | Flame retardant polymers | PFAS, PCBP1, AFF4 | ESR1 3038/4885ESR2 3597/4885TDP1 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.