Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381254 | 0.86 | ESR1 (0.83) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL11869306 | 0.84 | TSHR (0.59) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL9667816 | 0.78 | TSHR (0.50) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL8525796 | 0.77 | TSHR (0.55) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL11869299 | 0.76 | TSHR (0.49) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL27300404 | 0.76 | TSHR (0.42) | TSHRMAPK1TDP1LMNATP53 | |
| Chlorophenothane SCHEMBL7181 | 0.74 | TSHR (1.00) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL28443758 | 0.74 | TSHR (0.46) | TSHRMAPK1TDP1LMNATP53 | |
| Chlorophenothane SCHEMBL2065589 | 0.74 | TSHR (1.00) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL11050501 | 0.73 | ESR1 (0.55) | TSHRMAPK1LMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521280-A | Method for preparing 3,3', 4' -biphenyl tetracarboxylic acid and dianhydride thereof and obtained product | 中国石油化工股份有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-109134716-B | Vanadium catalyst and method for preparing olefin polymer | 北京引发科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111832895-A | Coastal wetland ecological vulnerability potential risk assessment method based on gray weighted relevance | 中国水产科学研究院黄海水产研究所 | 2020-10-27 | — | — | CN | claimed |
| EP-0519807-B1 | Process for the dehydrochlorination of 1,1-bis(R-phényl)-2,2,2-trichloroethanes | ATOCHEM ELF SA (FR) | 1995-08-09 | — | — | EP | claimed |
| US-5292409-A | Electrolytically generating superoxide ion under protective layer of ion exchange material | CAPE COD RESEARCH, INC. (US) | 1994-03-08 | — | — | US | claimed |
| US-5243110-A | DEHYDROCHLORINATION OF 1,1-BIS(R-PHENYL)-2,2,2-TRICHLOROETHANES | ELF ATOCHEM S.A. (FR) | 1993-09-07 | — | — | US | claimed |
| EP-0519807-A1 | Process for the dehydrochlorination of 1,1-bis(R-phényl)-2,2,2-trichloroethanes | ELF ATOCHEM S.A. (FR) | 1992-12-23 | — | — | EP | claimed |
| US-3932527-A | CONDENSATION OF CHLORAL WITH A BENZENE, ACID CATALYST | UNIVERSITY OF ILLINOIS FOUNDATION (US) | 1976-01-13 | — | — | US | claimed |
| JP-6234674-A | — | — | None | — | — | JP | disclosed |
| JP-6234674-A | — | — | None | — | — | JP | disclosed |
| CN-122070296-A | Insect neuropeptide analogs | 索拉斯塔生物有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122070295-A | Insect neuropeptide analogs | 索拉斯塔生物有限公司 | 2026-05-19 | — | — | CN | disclosed |
| US-11570987-B2 | Pesticidal compounds and methods of use | NEW YORK UNIVERSITY (US) | 2023-02-07 | — | — | US | disclosed |
| CN-115521280-A | Method for preparing 3,3', 4' -biphenyl tetracarboxylic acid and dianhydride thereof and obtained product | 中国石油化工股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| EP-0057153-A2 | Biocidal substances containing emulsifiable concentrates, aqueous emulsions obtained therefrom and utilization thereof for treating wood | XYLOCHIMIE (FR) | 1982-08-04 | — | — | EP | disclosed |
| EP-0055476-A1 | Degradation of halogenated carbon compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1982-07-07 | — | — | EP | disclosed |
| US-4192957-A | DEHYDROCHLORINATION OF 1,1,1-TRICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHANE TO 1,1-DICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHYLENE WITH LIQUID AMMONIA AND ALKYL AMINE HYDROHALIDE PROMOTER | GENERAL ELECTRIC COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4192956-A | DEHYDROCHLORINATION OF 1,1,1-TRICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHANE TO 1,1-DICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHYLENE WITH LIQUID AMMONIA AND INORGANIC HALIDE PROMOTER | GENERAL ELECTRIC COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4178466-A | Process for preparing phenyl trichloro-ethanes | GENERAL ELECTRIC COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4105857-A | CONDENSING PHENOL AND CHLORAL IN A SULFURIC ACID- METHYLENE CHLORIDE SOLVENT SYSTEM | GENERAL ELECTRIC COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11570987-B2 | Pesticidal compounds and methods of use | ACHE, DDT, PTMS | TSHR 2895/4885MAPK1 4348/4885TDP1 2973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.