Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851619 | 0.87 | KMT2A (0.67) | KMT2APOLBRAD52CDC25BALDH1A1 | |
| SCHEMBL27804272 | 0.81 | KMT2A (0.49) | KMT2APOLBRAD52CDC25BCD38 | |
| Methyl Phosphonate SCHEMBL4387220 | 0.78 | TOP2A (0.42) | POLBRAD52HDAC1 | |
| Methyl Phosphonate SCHEMBL4397039 | 0.75 | KCNH3 (0.41) | KMT2APOLBRAD52ALDH1A1KDM4E | |
| SCHEMBL11640078 | 0.71 | TSHR (0.60) | KMT2AALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL18415472 | 0.71 | KMT2A (0.54) | KMT2AALDH1A1HPGDKDM4ESMN1; SMN2 | |
| Anthracene SCHEMBL28304429 | 0.70 | PTPN1 (0.47) | KMT2AACP3ALDH1A1HPGDKDM4E | |
| SCHEMBL1868598 | 0.70 | RAD52 (1.00) | KMT2APOLBRAD52ALDH1A1HPGD | |
| Methyl Phosphonate SCHEMBL5686064 | 0.70 | HDAC6 (0.40) | KMT2AACP3ALDH1A1HPGDKDM4E | |
| SCHEMBL6858682 | 0.69 | ALDH1A1 (0.44) | KMT2APOLBRAD52ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101730565-B | Substituted phosphonates and their use for reducing amyloid aggregates | QUEEN MARY & WESTFIELD COLLEGE | 2015-06-10 | — | — | CN | disclosed |
| US-7629379-B2 | Substituted phosphonate fluorescent sensors and use thereof | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2009-12-08 | — | — | US | disclosed |
| US-20070049761-A1 | Substituted phosphonate fluorescent sensors and use thereof | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2007-03-01 | — | — | US | disclosed |
| EP-1625134-A2 | SUBSTITUTED PHOSPHONATE FLUORESCENT SENSORS AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101579-A2 | SUBSTITUTED PHOSPHONATE FLUORESCENT SENSORS AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049761-A1 | Substituted phosphonate fluorescent sensors and use thereof | NR2E3, CASR, NR3C2 | KMT2A 3756/4885POLB 2167/4885RAD52 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.