Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15619097 | 0.98 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL4014511 | 0.92 | LMNA (0.40) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL12597463 | 0.87 | PAOX (0.41) | ALDH1A1TSHRLMNAFNTAFNTB | |
| SCHEMBL8398329 | 0.85 | CA2 (0.46) | ALDH1A1TSHRLMNAALOX15RECQL | |
| SCHEMBL4952312 | 0.85 | CA2 (0.46) | ALDH1A1TSHRLMNAALOX15RECQL | |
| SCHEMBL23291930 | 0.85 | CA2 (0.46) | ALDH1A1TSHRLMNAALOX15RECQL | |
| SCHEMBL2735589 | 0.85 | CA2 (0.46) | ALDH1A1TSHRLMNAALOX15RECQL | |
| SCHEMBL14779178 | 0.85 | CA2 (0.46) | ALDH1A1TSHRLMNAALOX15RECQL | |
| SCHEMBL5238163 | 0.84 | CA2 (0.40) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL575713 | 0.83 | CA2 (0.44) | ALDH1A1TSHRLMNAALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658503-B1 | CHEMILUMINESCENT COMPOUNDS | MOLECULAR LIGHT TECH RES LTD (GB) | 2009-11-18 | — | — | EP | disclosed |
| EP-1658503-A1 | CHEMILUMINESCENT COMPOUNDS | Molecular Light Technology Research Limited (GB) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005022161-A1 | CHEMILUMINESCENT COMPOUNDS | MOLECULAR LIGHT TECHNOLOGY RESEARCH LIMITED (GB) | 2005-03-10 | — | — | WO | disclosed |