SCHEMBL438139

SCHEMBL438139

Cc1ccc(-c2ccc(N)c(N)c2)cc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.70
MEN1 O00255 1/20 0.70
KMT2A Q03164 1/20 0.70
CYP3A4 P08684 8/20 0.61
TSHR P16473 6/20 0.61
ALDH1A1 P00352 5/20 0.61
CASP1 P29466 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.50
ALOX15 P16050 2/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
KCNH2 Q12809 2/20 0.48
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.45
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43
HPGD P15428 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6866139 0.92 CYP3A4 (0.62) TDP1MEN1KMT2ACYP3A4TSHR
SCHEMBL31661348 0.92 CYP3A4 (0.62) TDP1MEN1KMT2ACYP3A4TSHR
SCHEMBL12957394 0.88 TDP1 (0.67) TDP1MEN1KMT2ACYP3A4TSHR
SCHEMBL4277577 0.88 CYP3A4 (0.81) TDP1MEN1KMT2ACYP3A4TSHR
SCHEMBL13862442 0.85 ALDH1A1 (0.61) TDP1MEN1KMT2ACYP3A4TSHR
Ethane SCHEMBL1599237 0.84 TDP1 (0.88) TDP1MEN1KMT2ACYP3A4TSHR
Methylamine SCHEMBL28942219 0.84 TDP1 (0.88) TDP1MEN1KMT2ACYP3A4TSHR
SCHEMBL23855 0.84 TDP1 (1.00) TDP1MEN1KMT2ACYP3A4TSHR
SCHEMBL29349835 0.84 TDP1 (1.00) TDP1MEN1KMT2ACYP3A4TSHR
Sulfur Dioxide SCHEMBL22009680 0.83 ALDH1A1 (0.52) TDP1MEN1KMT2ACYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912825-B2 Polymers derived from 2,2′-bisimidazoles THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2024-02-27 US disclosed
WO-2022210788-A1 PHOTOSENSITIVE RESIN COMPOSITION 味の素株式会社 2022-10-06 WO disclosed
US-9470058-B2 Ultra high temperature packer by high-temperature elastomeric polymers SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-10-18 US disclosed
US-9156008-B2 Cardo copolybenzimidazoles, gas separation membranes and preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-10-13 US disclosed
US-20140224124-A1 CARDO COPOLYBENZIMIDAZOLES, GAS SEPARATION MEMBRANES AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-14 US disclosed
US-8436106-B2 Crosslinkers and materials produced using them SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2013-05-07 US disclosed
US-8410185-B2 Porous polymeric materials for hydrogen storage UCHICAGO ARGONNE, LLC (US) 2013-04-02 US disclosed
US-20120065289-A1 POROUS POLYMERIC MATERIALS FOR HYDROGEN STORAGE UCHICAGO ARGONNE LLC 2012-03-15 US disclosed
US-20110139466-A1 ULTRA HIGH TEMPERATURE PACKER BY HIGH-TEMPERATURE ELASTOMERIC POLYMERS SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2011-06-16 US disclosed
US-20100022718-A1 CROSSLINKERS AND MATERIALS PRODUCED USING THEM SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2010-01-28 US disclosed
US-7601873-B2 Method of manufacturing 3,3′,4,4′-tetraaminobiphenyl SHOWA DENKO K.K. (JP) 2009-10-13 US disclosed
US-7211203-B2 Polymer electrolyte, proton conductive membrane and membrane-electrode assembly HONDA MOTOR CO., LTD. (JP) 2007-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912825-B2 Polymers derived from 2,2′-bisimidazoles PARG, PARN, NOP2 TDP1 1218/4885MEN1 2984/4885KMT2A 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.