Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386328 | 0.80 | HRH3 (0.39) | — | |
| SCHEMBL14422106 | 0.79 | ALDH1A1 (0.35) | MAPT | |
| SCHEMBL4383756 | 0.78 | L3MBTL3 (0.40) | — | |
| SCHEMBL14401675 | 0.72 | HRH3 (0.43) | CHRM5ADRA2CMAPTTP53THRB | |
| SCHEMBL4384271 | 0.71 | CHRM5 (0.40) | CHRM5ADRA2CMAPTTP53THRB | |
| SCHEMBL4389771 | 0.69 | RAD52 (0.38) | CHRM5ADRA2CMAPTTP53THRB | |
| SCHEMBL14401648 | 0.69 | CHRM5 (0.37) | CHRM5ADRA2CMAPTTP53THRB | |
| SCHEMBL6187561 | 0.66 | ALDH1A1 (0.36) | MAPTTP53SMN1; SMN2 | |
| SCHEMBL3165975 | 0.66 | CHRM5 (0.57) | CHRM5ADRA2CMAPTTP53THRB | |
| SCHEMBL12506852 | 0.66 | CHRM5 (0.52) | CHRM5ADRA2CMAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | CHRM5 3355/4885ADRA2C 3273/4885MAPT 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.