Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.95 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.95 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.95 |
| ▸ | FAAH | O00519 | 1/20 | 0.95 |
| ▸ | ELANE | P08246 | 1/20 | 0.95 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.95 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethylsulfonylfluoride SCHEMBL24938 | 0.97 | PRSS1 (1.00) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL3965163 | 0.97 | PRSS1 (1.00) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL11616357 | 0.95 | PRSS1 (0.95) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL4869292 | 0.95 | PRSS1 (0.95) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL28507854 | 0.91 | PRSS1 (0.86) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL11618045 | 0.87 | PRSS1 (0.79) | PRSS1PRSS2PRSS3FAAHELANE | |
| (Phenylsulfonyl)Benzene SCHEMBL11134052 | 0.87 | PRSS1 (0.79) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL7987561 | 0.87 | PRSS1 (0.79) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL27917976 | 0.85 | PRSS1 (0.76) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL6459388 | 0.84 | FAAH (0.75) | PRSS1PRSS2PRSS3FAAHELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420794-B2 | Anti-influenza M2e antibody | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120064085-A1 | ANTI-INFLUENZA M2e ANTIBODY | LOS ALAMOS NATIONAL SECURITY, LLC | 2012-03-15 | — | — | US | disclosed |