Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 4/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 4/20 | 1.00 |
| ▸ | DRD3 | P35462 | 4/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 3/20 | 1.00 |
| ▸ | DRD1 | P21728 | 3/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 3/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | BCL2 | P10415 | 1/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.97 |
| ▸ | TSHR | P16473 | 1/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.97 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorcyclizine SCHEMBL12157065 | 1.00 | KCNH2 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| Chlorcyclizine SCHEMBL13724147 | 1.00 | KCNH2 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| Chlorcyclizine SCHEMBL16769331 | 1.00 | KCNH2 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| Chlorcyclizine SCHEMBL321657 | 0.98 | CYP2D6 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| Homochlorcyclizine SCHEMBL30402 | 0.94 | DRD3 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| SCHEMBL2056217 | 0.93 | CHRM2 (0.86) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| Homochlorcyclizine SCHEMBL1977999 | 0.92 | SMN1; SMN2 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| Homochlorcyclizine SCHEMBL122573 | 0.92 | SMN1; SMN2 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| SCHEMBL7668121 | 0.91 | CHRM2 (0.83) | KCNH2CHRM2ADRA2ADRD3CHRM1 | |
| Cyclizine SCHEMBL4690 | 0.89 | CYP2D6 (1.00) | KCNH2CHRM2ADRA2ADRD3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4551 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026105164-A1 | NON-AQUEOUS LIQUID FORMULATIONS OF TETRACYCLINE ANTIBIOTICS | ETICO LIFESCIENCES PRIVATE LIMITED (IN) | 2026-05-21 | — | — | WO | claimed |
| US-20260060977-A1 | COMPOSITIONS AND METHODS FOR TREATING PROTOPORPHYRIA | UNIV RUTGERS (US) | 2026-03-05 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| EP-3441087-B1 | METHODS OF TREATING CHRONIC PAIN | TEVA PHARMACEUTICALS INT GMBH (CH) | 2025-02-19 | — | — | EP | claimed |
| CN-118647367-A | Novel injectable combination formulations | 南爱克萨股份公司 | 2024-09-13 | — | — | CN | claimed |
| CN-118512401-A | Lipid vesicle compositions with permeation enhancers | 迪迪艾斯研究公司 | 2024-08-20 | — | — | CN | claimed |
| CN-115175667-B | Lipid vesicle compositions with permeation enhancers | 迪迪艾斯研究公司 | 2024-06-04 | — | — | CN | claimed |
| US-20230420110-A1 | METHODS FOR OBJECTIVE ASSESSMENT, RISK PREDICTION, MATCHING TO EXISTING MEDICATIONS AND NEW METHODS OF USING DRUGS, AND MONITORING RESPONSES TO TREATMENTS FOR MOOD DISORDERS | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2023-12-28 | — | — | US | claimed |
| CN-116898824-A | Histamine H1 receptor antagonist slow-release nanoparticle, preparation method thereof, injection and application | 南方医科大学第三附属医院（广东省骨科研究院） | 2023-10-20 | — | — | CN | claimed |
| EP-4247259-A1 | METHODS FOR OBJECTIVE ASSESSMENT, RISK PREDICTION, MATCHING TO EXISTING MEDICATIONS AND NEW METHODS OF USING DRUGS, AND MONITORING RESPONSES TO TREATMENTS FOR MOOD DISORDERS | Indiana University Research and Technology Corporation (US) | 2023-09-27 | — | — | EP | claimed |
| EP-0449427-A2 | Use of an antihistamine in the treatment of alcohol intoxication | CLIDET NO 12 (PROPRIETARY) LIMITED (ZA) | 1991-10-02 | — | — | EP | claimed |
| US-4996047-A | Sustained release drug-resin complexes | RICHARDSON-VICKS, INC. (US) | 1991-02-26 | — | — | US | claimed |
| EP-0367746-A2 | Sustained release drug-resin complexes | RICHARDSON-VICKS, INC. (US) | 1990-05-09 | — | — | EP | claimed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | claimed |
| US-4729997-A | ANTIEMETICS, ANTIHISTAMINES | NASTECH PHARMACEUTICAL CO., INC. (US) | 1988-03-08 | — | — | US | claimed |
| EP-0201537-A4 | NOVEL USE OF ANTI-NAUSEA AND ANTI-EMETIC PHARMAZEUTICAL AGENTS. | NASTECH PHARM CO (US) | 1987-07-06 | — | — | EP | claimed |
| EP-0201537-A1 | NOVEL USE OF ANTI-NAUSEA AND ANTI-EMETIC PHARMAZEUTICAL AGENTS. | NASTECH PHARM CO (US) | 1986-11-20 | — | — | EP | claimed |
| WO-1986002553-A1 | NOVEL METHOD OF ADMINISTERING ANTI-NAUSEA AND ANTI-EMETIC PHARMACEUTICAL AGENTS AND NOVEL DOSAGE FORMS CONTAINING SAME | NASTECH PHARMACEUTICAL COMPANY, INC. (US) | 1986-05-09 | — | — | WO | claimed |
| US-4104382-A | (((THIAZOLYL-, ISOTHIAZOLYL- OR PYRIDYLALKYL)THIO)ALKYL)GUANIDINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-08-01 | — | — | US | claimed |
| US-4000302-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-12-28 | — | — | US | claimed |