Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646777 | 0.83 | CYP1A2 (0.46) | CYP1A2SLC29A1HIF1AADORA2AADORA3 | |
| SCHEMBL3654018 | 0.83 | PNP (0.56) | HIF1APNPLMNATP53HTT | |
| SCHEMBL2057069 | 0.83 | ADORA3 (0.57) | SLC29A1HIF1AADORA2AADORA3NT5E | |
| SCHEMBL16555219 | 0.83 | ADORA3 (0.57) | SLC29A1HIF1AADORA2AADORA3NT5E | |
| SCHEMBL6692360 | 0.83 | CYP1A2 (0.60) | CYP1A2ALDH1A1HIF1AADORA2AADORA3 | |
| SCHEMBL6858256 | 0.82 | CYP1A2 (0.45) | CYP1A2SLC29A1HIF1AADORA2AADORA3 | |
| SCHEMBL4370984 | 0.82 | CYP1A2 (0.45) | CYP1A2SLC29A1NT5EPNPLMNA | |
| SCHEMBL98907 | 0.75 | ADORA3 (0.53) | ADORA3NT5EPNPPDE3A | |
| SCHEMBL13833321 | 0.75 | ADORA3 (0.53) | ADORA3NT5EPNPPDE3A | |
| SCHEMBL18759056 | 0.75 | ADORA3 (0.53) | ADORA3NT5EPNPPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010659-A2 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | Epicentre Technologies (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007120863-A2 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | EPICENTRE TECHNOLOGIES (US) | 2007-10-25 | — | — | WO | claimed |
| EP-0350287-A2 | Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use | NeXstar Pharmaceuticals, Inc. (US) | 1990-01-10 | — | — | EP | claimed |