Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383154 | 0.83 | CYP1A2 (0.41) | CYP1A2ALDH1A1LMNAPNPTP53 | |
| SCHEMBL3654018 | 0.83 | PNP (0.56) | LMNAPNPTP53HTTPDE4D | |
| SCHEMBL19325462 | 0.82 | CYP1A2 (0.67) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL4409629 | 0.81 | CYP1A2 (0.66) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL16555219 | 0.78 | ADORA3 (0.57) | LMNAMAPK1SMN1; SMN2ADORA3ADORA1 | |
| SCHEMBL2057069 | 0.78 | ADORA3 (0.57) | LMNAMAPK1SMN1; SMN2ADORA3ADORA1 | |
| SCHEMBL8104283 | 0.74 | ALDH1A1 (0.70) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL3162 | 0.74 | ALDH1A1 (0.70) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL16695889 | 0.74 | ALDH1A1 (0.70) | CYP1A2ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL13833316 | 0.74 | ALDH1A1 (0.70) | CYP1A2ALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003072757-A9 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA INC (US) | 2004-10-21 | — | — | WO | claimed |