SCHEMBL4383217

SCHEMBL4383217

CC(=O)OC(F)(F)C1CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 2/20 0.32
EPHX2 P34913 2/20 0.31
USP2 O75604 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3363555 0.83 KDM4E (0.34) KDM4ELMNAALDH1A1
SCHEMBL3364848 0.82 KDM4E (0.37) KDM4ELMNAALDH1A1USP2TDP1
SCHEMBL25840117 0.74 GAA (0.31)
SCHEMBL4387300 0.73 USP2 (0.33) ALDH1A1USP2TDP1
SCHEMBL3363142 0.72 KDM4E (0.35) KDM4ELMNAALDH1A1EPHX2TDP1
SCHEMBL3364410 0.71 KDM4E (0.34) KDM4ELMNAALDH1A1TDP1
SCHEMBL4398284 0.71 KDM4E (0.33) KDM4ELMNAALDH1A1USP2TDP1
SCHEMBL4385013 0.70 EPHX2 (0.36) KDM4ELMNAALDH1A1EPHX2USP2
SCHEMBL3367444 0.70 KDM4E (0.32) KDM4ELMNAALDH1A1USP2TDP1
SCHEMBL3365779 0.70 KDM4E (0.32) KDM4ELMNAALDH1A1USP2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed