SCHEMBL4387300

SCHEMBL4387300

CC(C)(C)OC(F)(F)C1CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13259999 0.77 ALDH1A1 (0.36) USP2ALDH1A1TDP1
SCHEMBL13532353 0.74 ALDH1A1 (0.35) USP2ALDH1A1TDP1
SCHEMBL11921079 0.74 ALDH1A1 (0.35) USP2ALDH1A1TDP1
SCHEMBL4383217 0.73 KDM4E (0.36) USP2ALDH1A1TDP1
SCHEMBL24643274 0.72 LMNA (0.34) USP2ALDH1A1TDP1
SCHEMBL203770 0.72 LMNA (0.34) USP2ALDH1A1TDP1
SCHEMBL4602458 0.72 ALDH1A1 (0.38) USP2ALDH1A1TDP1
SCHEMBL3366163 0.72 ALDH1A1 (0.32) USP2ALDH1A1TDP1
SCHEMBL119840 0.71 ALDH1A1 (0.39) USP2ALDH1A1TDP1
SCHEMBL8402115 0.69 ALDH1A1 (0.35) USP2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed