SCHEMBL4385013

SCHEMBL4385013

CCC(=O)OC(C1CC2C=CC1C2)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.36
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3363555 0.83 KDM4E (0.34) KDM4ELMNAALDH1A1
SCHEMBL4398284 0.81 KDM4E (0.33) KDM4ELMNAUSP2ALDH1A1TDP1
SCHEMBL3367444 0.79 KDM4E (0.32) KDM4ELMNAUSP2ALDH1A1TDP1
SCHEMBL14448861 0.78 CYP11B1 (0.31) EPHX2USP2ALDH1A1TDP1
SCHEMBL14468507 0.75 LMNA (0.33) EPHX2KDM4ELMNAALDH1A1
SCHEMBL444687 0.74 USP2 (0.30) USP2ALDH1A1TDP1
SCHEMBL14598915 0.72 KDM4E (0.32) KDM4ELMNA
SCHEMBL4383053 0.71
SCHEMBL4383217 0.70 KDM4E (0.36) EPHX2KDM4ELMNAUSP2ALDH1A1
SCHEMBL6330830 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed