Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAT | P00750 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134885 | 0.84 | TTR (0.61) | TTRSELLSELPSELEPLAU | |
| SCHEMBL129716 | 0.82 | SELL (0.58) | SELLSELPSELEALDH1A1KMT2A | |
| SCHEMBL18751667 | 0.80 | SELL (0.65) | TTRSELLSELPSELEPLAU | |
| SCHEMBL12588326 | 0.77 | SELL (0.68) | SELLSELPSELEALDH1A1KMT2A | |
| SCHEMBL815630 | 0.77 | ALDH1A1 (0.54) | TTRSELLSELPSELEPLAU | |
| SCHEMBL13349219 | 0.75 | HDAC1 (0.35) | SELLSELPSELEPLAUF2 | |
| SCHEMBL2209559 | 0.75 | RAPGEF4 (0.39) | SELLSELPSELEPLAUF2 | |
| SCHEMBL12217591 | 0.75 | ALDH1A1 (0.52) | SELLSELPSELEALDH1A1KMT2A | |
| SCHEMBL11747447 | 0.75 | TTR (0.65) | TTRALBKMT2ALMNAMEN1 | |
| SCHEMBL815794 | 0.75 | ERN1 (0.46) | TTRALBKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069532-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2018-04-19 | — | — | WO | disclosed |
| EP-1409441-B1 | INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY | MERCK PATENT GMBH (DE) | 2009-11-18 | — | — | EP | disclosed |
| US-7122228-B2 | Transistros; liquid crystals display; electrooptics | MERCK PATENT GMBH (DE) | 2006-10-17 | — | — | US | disclosed |
| US-20040171866-A1 | Transistros; liquid crystals display; electrooptics | MERCK PATENTGESELLSCHAFT (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171866-A1 | Transistros; liquid crystals display; electrooptics | VCL, RIF1, IPO11 | TTR 34/4885SELL 2386/4885SELP 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.