Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85548 | 0.93 | AKR1C3 (0.71) | MAPTAKR1C3LMNAKDM4EGAA | |
| SCHEMBL19221687 | 0.89 | MAPT (0.65) | MAPTAKR1C3LMNAKDM4EGAA | |
| SCHEMBL378458 | 0.86 | MAPT (0.96) | MAPTAKR1C3LMNAGAAALDH1A1 | |
| SCHEMBL1851861 | 0.86 | MAPT (0.89) | MAPTAKR1C3LMNAGAAALDH1A1 | |
| SCHEMBL5123709 | 0.85 | MAPT (0.52) | MAPTAKR1C3KDM4EGAABLM | |
| SCHEMBL7048817 | 0.84 | MAPT (0.85) | MAPTAKR1C3LMNAGAAALDH1A1 | |
| SCHEMBL85552 | 0.84 | MAPT (1.00) | MAPTAKR1C3LMNAGAAALDH1A1 | |
| SCHEMBL6607374 | 0.84 | MAPT (1.00) | MAPTAKR1C3LMNAGAAALDH1A1 | |
| SCHEMBL223626 | 0.84 | MAPT (1.00) | MAPTAKR1C3LMNAGAAALDH1A1 | |
| SCHEMBL9647832 | 0.84 | MITF (0.70) | MAPTAKR1C3KDM4EGAABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899331-B1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-1899331-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000644-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-04 | — | — | WO | disclosed |