Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.68 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607374 | 1.00 | MAPT (1.00) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL85552 | 1.00 | MAPT (1.00) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL378458 | 0.98 | MAPT (0.96) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL1851861 | 0.94 | MAPT (0.89) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL7048817 | 0.92 | MAPT (0.85) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL9649952 | 0.90 | MAPT (0.81) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL6151230 | 0.90 | SIRT6 (0.81) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL15271381 | 0.90 | SIRT6 (0.81) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL14504224 | 0.88 | MAPT (0.78) | MAPTLMNAALDH1A1SIRT6POLB | |
| SCHEMBL9651198 | 0.88 | MAPT (0.77) | MAPTLMNAALDH1A1SIRT6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-12-22 | — | — | US | claimed |
| WO-2010097815-A2 | A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| US-7732534-B2 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2010-06-08 | — | — | US | claimed |
| US-20080051552-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION | 2008-02-28 | — | — | US | claimed |
| US-20080051519-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | claimed |
| EP-1738800-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1738801-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1559404-A1 | Dyeing composition for keratininous fibres which contains an alcohol oxidase and an acidic direct dye or a salt thereof | L'OREAL (FR) | 2005-08-03 | — | — | EP | claimed |
| CN-120369927-B | Use of metabolic markers for the preparation of products for monitoring heart failure and products | 中日友好医院(中日友好临床医学研究所) | 2025-11-11 | — | — | CN | disclosed |
| CN-120369927-A | Use of metabolic markers for the preparation of products for monitoring heart failure and products | 中日友好医院(中日友好临床医学研究所) | 2025-07-25 | — | — | CN | disclosed |
| WO-2023213211-A9 | 2,4-DISUBSTITUTED-5-FLUOROPYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 长沙晶易医药科技股份有限公司 | 2024-03-21 | — | — | WO | disclosed |
| CN-115215816-B | Synthesis method of lactam compound | 普济生物科技（台州）有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023213211-A1 | 2,4-DISUBSTITUTED-5-FLUOROPYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 长沙晶易医药科技股份有限公司 | 2023-11-09 | — | — | WO | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |
| US-3947434-A | 9-(P-phenylazoanilino)-7-methyl-1H-imidazo[4,5-f]quinolines | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | HCN2, RAC2, HCN1 | MAPT 3456/4885LMNA 2308/4885ALDH1A1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.