Fluoride

Fluoride

SCHEMBL4383957

CCCCN(CCCC)c1ccc(OC)c2c1N2.F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
SLC16A3 O15427 1/20 0.33
SLC16A1 P53985 1/20 0.33
CRHR1 P34998 5/20 0.32
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL3362188 0.79 CRHR1 (0.33) CRHR1
Fluoride SCHEMBL22444652 0.74 ALDH1A1 (0.33) CRHR1
Fluoride SCHEMBL4390276 0.73 ALDH1A1 (0.35) CRHR1
SCHEMBL513559 0.72 HSD17B10 (0.40) MEN1TSHRKMT2ACYP1A2CYP3A4
SCHEMBL1573613 0.71 CYP1A2 (0.47) CYP1A2CYP3A4CYP2D6CYP2C19CRHR1
SCHEMBL9810814 0.71 CA12 (0.46) MEN1TSHRKMT2ACYP1A2SLC16A3
SCHEMBL12860226 0.69 CYP1A2 (0.44) CYP1A2CYP3A4CYP2D6CYP2C19CRHR1
Fluoride SCHEMBL4577949 0.69 CRHR1 (0.33) MEN1KMT2ACYP3A4CYP2D6CYP2C19
SCHEMBL16248320 0.68 SLC16A3 (0.47) SLC16A3SLC16A1CRHR1NR1H2NR1H3
SCHEMBL10009760 0.66 CRHR1 (0.46) CYP1A2CYP3A4CYP2D6CYP2C19CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP claimed
EP-2954373-B1 CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS US INC (US) 2019-04-24 EP disclosed
EP-2954373-A1 CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL Fujifilm Hunt Chemicals US, Inc. (US) 2015-12-16 EP disclosed
WO-2014124052-A1 CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS, INC. (US) 2014-08-14 WO disclosed
US-20130216947-A1 CHEMICAL COATING COMPOSITION FOR FORMING A LASER-MARKABLE MATERIAL AND A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS U.S.A., INC. 2013-08-22 US disclosed
WO-2013109268-A1 CHEMICAL COATING COMPOSITION FOR FORMING A LASER-MARKABLE MATERIAL AND A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS U.S.A., INC. (US) 2013-07-25 WO disclosed
US-20130183620-A1 CHEMICAL COATING COMPOSITION FOR FORMING A LASER-MARKABLE MATERIAL AND A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS U.S.A., INC. 2013-07-18 US disclosed
US-7576036-B2 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-7410744-B2 Recording method FUJIFILM CORPORATION (JP) 2008-08-12 US disclosed
US-20070128542-A1 Recording method FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070098900-A1 Media providing non-contacting formation of high contrast marks and method of using same, composition for forming a laser-markable coating, a laser-markable material and process of forming a marking FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. 2007-05-03 US disclosed
US-20070032381-A1 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2007-02-08 US disclosed
US-7153812-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-12-26 US disclosed
US-20040192548-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2004-09-30 US disclosed
US-6797318-B2 PROTECTIVE COATING CONTAINING AMIDE COMPOUND AND WATER SOLUBLE POLYMER IMPROVES HEAD-MATCHING PROPERTY; MATERIALS HANDLING FUJI PHOTO FILM CO., LTD. (JP) 2004-09-28 US disclosed
US-4583104-A Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed