Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016831 | 0.80 | MAPT (0.56) | LMNAHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL9016803 | 0.77 | TBXA2R (0.44) | LMNASMN1; SMN2FFAR1PKMMAPT | |
| SCHEMBL3056174 | 0.76 | GRM2 (0.46) | PRMT1CYP2C9ATMLMNAKMT2A | |
| SCHEMBL3056170 | 0.76 | GRM2 (0.46) | PRMT1CYP2C9ATMLMNAKMT2A | |
| SCHEMBL31537531 | 0.76 | GRM2 (0.46) | PRMT1CYP2C9ATMLMNAKMT2A | |
| SCHEMBL9016801 | 0.76 | TBXA2R (0.46) | CYP2C9L3MBTL1TSHRNPSR1FFAR1 | |
| SCHEMBL9090735 | 0.76 | GRM1 (0.42) | LMNAKMT2AMEN1FFAR1PKM | |
| SCHEMBL5338882 | 0.73 | LMNA (0.52) | CYP2C9ATMMAOAMAOBLMNA | |
| SCHEMBL11377698 | 0.72 | PRMT1 (0.45) | PRMT1CYP2C9ATMLMNAKMT2A | |
| SCHEMBL9093729 | 0.72 | SMN1; SMN2 (0.49) | PRMT1CYP2C9LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | claimed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | claimed |
| WO-2007070092-A2 | METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME | PRYOG, LLC (US) | 2007-06-21 | — | — | WO | claimed |
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629400-B2 | Image making medium | HYMAN SYDNEY | 2009-12-08 | — | — | US | disclosed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | disclosed |
| WO-2007070092-A2 | METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME | PRYOG, LLC (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20030035917-A1 | Image making medium | HYMAN SYDNEY (US) | 2003-02-20 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5571825-A | Method of selectively inhibiting prostaglandin G/H synthase-2 | WARNER-LAMBERT COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5563169-A | INHIBITORS OF ACYLCOENZYME A:CHOLESTEROL TRANSFERASE, FOR TREATMENT AND/OR PREVENTION OF ATHEROSCLEROSIS | SANKYO COMPANY, LIMITED (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0636619-A1 | TRICYCLIC HETEROCYCLIC COMPOUND | SANKYO COMPANY LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |