SCHEMBL3056174

SCHEMBL3056174

N[C@@H](CSC1c2ccccc2Oc2ccccc21)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 3/20 0.46
PRMT1 Q99873 1/20 0.46
CYP2C9 P11712 1/20 0.45
GRM3 Q14832 1/20 0.45
ATM Q13315 2/20 0.45
KIF11 P52732 5/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
KMT2A Q03164 1/20 0.40
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
XIAP P98170 1/20 0.40
SLC7A5 Q01650 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3056170 1.00 GRM2 (0.46) GRM2PRMT1CYP2C9GRM3ATM
SCHEMBL31537531 1.00 GRM2 (0.46) GRM2PRMT1CYP2C9GRM3ATM
SCHEMBL3471771 0.83 KIF11 (0.48) KIF11ALPIPKMPTGS1XIAP
SCHEMBL3053149 0.81 ATM (0.39) GRM2PRMT1CYP2C9GRM3ATM
SCHEMBL14459215 0.81 KIF11 (0.47) KIF11ALPIPKMPTGS1XIAP
SCHEMBL14459222 0.79 KIF11 (0.51) KIF11
SCHEMBL14459219 0.79 KIF11 (0.45) KIF11ALPIPKMPTGS1XIAP
SCHEMBL11377698 0.78 PRMT1 (0.45) GRM2PRMT1CYP2C9GRM3ATM
SCHEMBL4384080 0.76 PRMT1 (0.48) PRMT1CYP2C9ATML3MBTL1LMNA
SCHEMBL3053147 0.75 PRMT1 (0.43) GRM2PRMT1CYP2C9GRM3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025079064-A1 INTERLEUKIN-17 PEPTIDOMIMETIC INHIBITORS PEPTICOM LTD. (IL) 2025-04-17 WO disclosed
US-7745392-B2 Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues NITTO DENKO CORPORATION (JP) 2010-06-29 US disclosed
US-20070078078-A1 Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues NITTO DENKO CORPORATION (JP) 2007-04-05 US disclosed
WO-2007038169-A2 MULTI-VALENT GUANIDINIUM COMPOUNDS FOR MOLECULAR TRANSLOCATION ACROSS CELLULAR MEMBRANES AND EPITHELIAL TISSUES NITTO DENKO CORPORATION (JP) 2007-04-05 WO disclosed
US-4267344-A 3-PENTA/ALKOXY/BENZYL-; -XANTHYL-, -THIOXANTHYL-, OR -SELENOXANTHYLOXAZOLIDINE-2,5-DIONES PROTEINKEMISK INSTITUT. TILKNYTTET AKADEMIET FOR DE TEKNISKE VIDENSKABER (DK) 1981-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078078-A1 Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues GLS, FABP2, GOLIM4 GRM2 442/4885PRMT1 824/4885CYP2C9 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.