Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280080 | 0.83 | MAPT (0.51) | MAPTXBP1LMNAALDH1A1PKM | |
| SCHEMBL8368744 | 0.81 | MAPT (0.47) | MAPTXBP1LMNAALDH1A1PKM | |
| SCHEMBL9016803 | 0.81 | TBXA2R (0.44) | MAPTXBP1LMNAALDH1A1PKM | |
| SCHEMBL9090735 | 0.80 | GRM1 (0.42) | MAPTXBP1LMNAALDH1A1PKM | |
| SCHEMBL4384080 | 0.80 | PRMT1 (0.48) | MAPTLMNAPKMSMN1; SMN2TSHR | |
| SCHEMBL9016801 | 0.80 | TBXA2R (0.46) | MAPTXBP1CYP1A2TSHRFFAR1 | |
| SCHEMBL8369184 | 0.76 | MAPT (0.44) | MAPTXBP1LMNAALDH1A1PKM | |
| SCHEMBL15505367 | 0.74 | ALDH1A1 (0.46) | MAPTALDH1A1CYP1A2TSHRCDC25B | |
| SCHEMBL3471771 | 0.74 | KIF11 (0.48) | MAPTXBP1PKMCYP1A2TSHR | |
| SCHEMBL9628724 | 0.73 | ALDH1A1 (0.41) | MAPTLMNAALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571825-A | Method of selectively inhibiting prostaglandin G/H synthase-2 | WARNER-LAMBERT COMPANY (US) | 1996-11-05 | — | — | US | disclosed |