Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 4-Vinylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 known ✓ | Q92731 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Vinylphenol SCHEMBL28941792 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Vinylphenol SCHEMBL4385918 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Vinylphenol SCHEMBL28399759 | 0.86 | TYR (0.54) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Vinylphenol SCHEMBL11251558 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Vinylphenol SCHEMBL8380331 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Hydroxyacetophenone SCHEMBL8726133 | 0.85 | HSD17B1 (0.61) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Vinylphenol SCHEMBL170622 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Vinylphenol SCHEMBL59328 | 0.85 | — | — | |
| 4-Vinylphenol SCHEMBL7740604 | 0.84 | TYR (0.63) | ALDH1A1KDM4ETYRCA12CA1 | |
| 4-Vinylphenol SCHEMBL8519569 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4ETYRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115612126-A | Cross-linked polystyrene solid acid catalyst with polymerization inhibition function and preparation method and application thereof | 江苏集萃光敏电子材料研究所有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-115612126-B | Crosslinked polystyrene solid acid catalyst with polymerization inhibition function, and preparation method and application thereof | 江苏集萃光敏电子材料研究所有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-115612126-A | Cross-linked polystyrene solid acid catalyst with polymerization inhibition function and preparation method and application thereof | 江苏集萃光敏电子材料研究所有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-105669889-A | Styrene derivative-methacrylate copolymer containing photo-acid generation groups as well as preparation and application of styrene derivative-methacrylate copolymer | 北京师范大学 | 2016-06-15 | — | — | CN | disclosed |
| US-7629400-B2 | Image making medium | HYMAN SYDNEY | 2009-12-08 | — | — | US | disclosed |
| US-20030035917-A1 | Image making medium | HYMAN SYDNEY (US) | 2003-02-20 | — | — | US | disclosed |
| US-5330627-A | Thermosetting coating compositions and their use | HERBERTS G.M.B.H. (DE) | 1994-07-19 | — | — | US | disclosed |