SCHEMBL4384468

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6504567	0.88	ALDH1A1 (0.50)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL4382362	0.79	MAPK14 (0.46)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL2707694	0.79	ALDH1A1 (0.56)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL4384906	0.78	ALDH1A1 (0.56)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL7737462	0.74	NR4A1 (0.65)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL13635225	0.73	ALDH1A1 (0.50)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL289398	0.73	LMNA (0.69)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL4390396	0.72	ALDH1A1 (0.50)	ALDH1A1LMNAMYC
	SCHEMBL26579409	0.71	LMNA (0.60)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL6498931	0.68	L3MBTL1 (0.44)	ALDH1A1KDM4ELMNAL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.