Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27573349 | 0.98 | NPC1 (0.62) | NPC1POLBALDH1A1RBP4MAPT | |
| Hydrochloric Acid SCHEMBL4392863 | 0.98 | NPC1 (0.62) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL15244373 | 0.86 | NPC1 (0.62) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL6081356 | 0.85 | NPC1 (0.61) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL7503700 | 0.83 | NPC1 (0.59) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL3759581 | 0.83 | POLB (0.59) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL6776473 | 0.83 | NPC1 (0.59) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL27335141 | 0.83 | ALDH1A1 (0.59) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL3692136 | 0.82 | NPC1 (0.58) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL9018351 | 0.82 | NPC1 (0.58) | NPC1POLBALDH1A1RBP4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167334-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | SHERMOLOVICH YURIY GRIGORIEVIC (UA) | 2004-08-26 | — | — | US | claimed |
| CN-1419542-A | Heterocyclic acylsulfimide compounds, process for their preparation, compositions containing them and their use as pesticides | BAYER CROSCIENCE GMBH (DE) | 2003-05-21 | — | — | CN | claimed |
| EP-1274683-A2 | HETEROCYCLIC ACYLSULFIMIDES, A METHOD FOR THEIR PRODUCTION, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2003-01-15 | — | — | EP | claimed |
| US-20020032328-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | AVENTIS CROPSCIENCE GMBH (DE) | 2002-03-14 | — | — | US | claimed |
| WO-2001070692-A2 | HETEROCYCLIC ACYLSULFIMIDES, A METHOD FOR THEIR PRODUCTION, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2001-09-27 | — | — | WO | claimed |
| CN-105753778-A | Synthesis method for 4-(trifluoromethyl)-2-(3-(trifluoromethyl)phenoxy)pyridine-3-amine | 常州大学 | 2016-07-13 | — | — | CN | disclosed |
| US-7629348-B2 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | MERIAL LIMITED (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629348-B2 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | MERIAL LIMITED (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080139627-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | BECKMANN MARION | 2008-06-12 | — | — | US | disclosed |
| US-20080139627-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | BECKMANN MARION | 2008-06-12 | — | — | US | disclosed |
| US-20080097099-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | BECKMANN MARION | 2008-04-24 | — | — | US | disclosed |
| US-20080097099-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | BECKMANN MARION | 2008-04-24 | — | — | US | disclosed |
| US-20040167334-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | SHERMOLOVICH YURIY GRIGORIEVIC (UA) | 2004-08-26 | — | — | US | disclosed |
| EP-1432313-A1 | N-THIO-NICOTINAMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-20030119852-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions, comprising them and their use as pesticides | BAYER CROPSCIENCE GMBH (GE) | 2003-06-26 | — | — | US | disclosed |
| CN-1419542-A | Heterocyclic acylsulfimide compounds, process for their preparation, compositions containing them and their use as pesticides | BAYER CROSCIENCE GMBH (DE) | 2003-05-21 | — | — | CN | disclosed |
| WO-2003028458-A1 | N-THIO-NICOTINAMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-04-10 | — | — | WO | disclosed |
| EP-1274683-A2 | HETEROCYCLIC ACYLSULFIMIDES, A METHOD FOR THEIR PRODUCTION, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2003-01-15 | — | — | EP | disclosed |
| US-20020032328-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | AVENTIS CROPSCIENCE GMBH (DE) | 2002-03-14 | — | — | US | disclosed |
| WO-2001070692-A2 | HETEROCYCLIC ACYLSULFIMIDES, A METHOD FOR THEIR PRODUCTION, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032328-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | DDT, PTMS, TMT1A | NPC1 4510/4885POLB 4249/4885ALDH1A1 768/4885 |
| US-20080139627-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | ACHE, DDT, PIR | NPC1 4481/4885POLB 4499/4885ALDH1A1 1482/4885 |
| US-20040167334-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | DDT, PTMS, TMT1A | NPC1 4510/4885POLB 4249/4885ALDH1A1 768/4885 |
| US-20030119852-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions, comprising them and their use as pesticides | ACHE, DDT, PIR | NPC1 4068/4885POLB 4414/4885ALDH1A1 504/4885 |
| US-20080097099-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | ACHE, DDT, PIR | NPC1 4551/4885POLB 4317/4885ALDH1A1 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.