Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386243 | 0.88 | MAPK1 (0.44) | KMT2ASMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL4379702 | 0.88 | EGFR (0.44) | KMT2AHPGDALDH1A1LMNAMEN1 | |
| SCHEMBL4386467 | 0.88 | MAPT (0.55) | KMT2ASMN1; SMN2NPC1ALDH1A1MEN1 | |
| SCHEMBL4384152 | 0.84 | ALDH1A1 (0.58) | KMT2AHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4386854 | 0.83 | TACR3 (0.52) | KMT2AALDH1A1MEN1RAB9AMAPT | |
| SCHEMBL6025387 | 0.82 | RAB9A (0.55) | KMT2AHPGDSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4386601 | 0.81 | ALDH1A1 (0.62) | KMT2AHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4380223 | 0.81 | SMN1; SMN2 (0.42) | KMT2AHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4394430 | 0.80 | ALDH1A1 (0.46) | KMT2AALDH1A1RAB9AMAPTHTT | |
| SCHEMBL4380891 | 0.79 | POLB (0.53) | KMT2ASMN1; SMN2ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669189-B1 | RESIN-COATED METAL PLATE AND DRAWN CAN USING THE SAME | TOYO SEIKAN KAISHA LTD (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-7538241-B2 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070155813-A1 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1704856-A1 | HSP90 FAMILY PROTEIN INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155813-A1 | Hsp90 family protein inhibitors | HSP90AB1, HEATR1, HSP90AB2P | KMT2A 3994/4885HPGD 3238/4885SMN1; SMN2 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.