Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 5/20 | 0.51 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176703 | 0.84 | TAOK1 (0.51) | TAOK1TAOK3OPRM1OPRD1OPRK1 | |
| SCHEMBL5668410 | 0.79 | LTA4H (0.48) | TRPV1CACNA1GCACNA1HCACNA1IMAPT | |
| SCHEMBL4388997 | 0.79 | CACNA1G (0.46) | TRPV1CACNA1GCACNA1HCACNA1IMAPT | |
| SCHEMBL5668902 | 0.78 | CACNA1G (0.44) | TAOK1TAOK3CACNA1GCACNA1HCACNA1I | |
| SCHEMBL2172285 | 0.78 | CACNA1G (0.45) | TAOK1TAOK3CACNA1GCACNA1HCACNA1I | |
| SCHEMBL2171492 | 0.78 | TRPV1 (0.56) | TRPV1CACNA1GCACNA1HCACNA1IKMT2A | |
| SCHEMBL12407135 | 0.78 | CACNA1G (0.47) | TAOK1TAOK3TRPV1CACNA1GCACNA1H | |
| SCHEMBL4386435 | 0.77 | CACNA1G (0.43) | TAOK1TAOK3CACNA1GCACNA1HCACNA1I | |
| SCHEMBL2171264 | 0.77 | NPC1 (0.55) | CACNA1GCACNA1HCACNA1IALDH1A1MAPT | |
| SCHEMBL4394082 | 0.77 | CACNA1G (0.43) | TAOK1TAOK3CACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186905-A1 | ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2009-07-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186905-A1 | ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE | ALK, BCL3, MCL1 | TAOK1 2409/4885TAOK3 1654/4885OPRM1 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.