SCHEMBL43848

SCHEMBL43848

CC(C(=O)S)C(=O)CN1C(=O)CCC1=O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ ALDH1A1 P00352 5/20 0.35
▸ ALOX12 P18054 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ GAA P10253 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ S1PR2 O95136 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ GFER P55789 1/20 0.31
▸ ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067000 0.80 TSHR (0.41) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL6277577 0.80 SMN1; SMN2 (0.38) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL18099940 0.77 TSHR (0.39) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL24829622 0.76 TSHR (0.38) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL6037020 0.73 SMN1; SMN2 (0.43) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL11507664 0.73 TSHR (0.36) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL1012561 0.72 SMN1; SMN2 (0.40) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL18932921 0.71 ALDH1A1 (0.36) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL17787230 0.69 ALDH1A1 (0.39) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12
SCHEMBL5091798 0.69 TSHR (0.44) TSHRSMN1; SMN2RAB9AALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 511 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035410-A1 THERAPEUTIC PEPTIDES AND METHODS OF PEPTIDE DESIGN WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2026-02-05 — — US claimed
EP-4626462-A1 GLUCOCEREBROSIDASE (GBA) POLYMER CONJUGATE, PREPARATION METHOD AND USE FOR NANOTECHNOLOGICAL BASED ENZYME REPLACEMENT THERAPY Fundació Hospital Universitari Vall Hebron - Institut de Recerca (ES) 2025-10-08 — — EP claimed
WO-2024115612-A1 GLUCOCEREBROSIDASE (GBA) POLYMER CONJUGATE, PREPARATION METHOD AND USE FOR NANOTECHNOLOGICAL BASED ENZYME REPLACEMENT THERAPY FUNDACIÓ HOSPITAL UNIVERSITARI VALL HEBRON - INSTITUT DE RECERCA (VHIR) (ES) 2024-06-06 — — WO claimed
US-20230270882-A1 PEPTIDE-NANOPARTICLE CONJUGATES WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-08-31 — — US claimed
US-11564995-B2 Peptide-nanoparticle conjugates WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-01-31 — — US claimed
CN-115087465-A Peptide-nanoparticle conjugates 威斯康星校友研究基金会 2022-09-20 — — CN claimed
US-20210393799-A1 DENDRITIC POLYMERS COMPLEXED WITH IMMUNE CHECKPOINT INHIBITORS FOR ENHANCED CANCER IMMUNOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION 2021-12-23 — — US claimed
CN-113613680-A Dendrimers complexed with immune checkpoint inhibitors for enhancing cancer immunotherapy 威斯康星校友研究基金会 2021-11-05 — — CN claimed
WO-2020092304-A9 DENDRITIC POLYMERS COMPLEXED WITH IMMUNE CHECKPOINT INHIBITORS FOR ENHANCED CANCER IMMUNOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-07-22 — — WO claimed
US-20210187120-A1 PEPTIDE-NANOPARTICLE CONJUGATES WISCONSIN ALUMNI RESEARCH FOUNDATION 2021-06-24 — — US claimed
JP-2011528106-A — — 2011-11-10 — — JP claimed
EP-2054439-B1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF PASTEUR INSTITUT (FR) 2011-06-01 — — EP claimed
EP-2318838-A1 HIGH CAPACITY SOLID PHASE Radiometer Medical ApS (DK) 2011-05-11 — — EP claimed
US-20110015368-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-01-20 — — US claimed
WO-2010006604-A1 HIGH CAPACITY SOLID PHASE RADIOMETER MEDICAL APS (DK) 2010-01-21 — — WO claimed
EP-2054439-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF INSTITUT PASTEUR (FR) 2009-05-06 — — EP claimed
WO-2008015273-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF INSTITUT PASTEUR (FR) 2008-02-07 — — WO claimed
US-7067322-B2 Fusion protein arrays on metal substrates for surface plasmon resonance imaging WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-06-27 — — US claimed
EP-0941738-B1 Antigenic conjugates of conserved lipooligosaccharides of gram negative bacteria WYETH CORP (US) 2005-05-11 — — EP claimed
EP-0382781-B1 COMPOSITION FOR TREATING CANCERS CHARACTERIZED BY OVER-EXPRESSION OF THE C-FMS PROTO-ONCOGENE GENETICS INSTITUTE, INC. (US) 1993-09-29 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015368-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF CD4, GPR180, GPR65 TSHR 1938/4885SMN1; SMN2 4518/4885RAB9A 4061/4885
US-20260035410-A1 THERAPEUTIC PEPTIDES AND METHODS OF PEPTIDE DESIGN MICA, IGSF11, TNFSF10 TSHR 165/4885SMN1; SMN2 1737/4885RAB9A 4281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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