Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848067 | 0.90 | HSP90AA1 (0.47) | CYP11B1CYP11B2AGTR2HSP90AA1HSP90AB1 | |
| SCHEMBL4386605 | 0.83 | CYP19A1 (0.47) | HSP90AA1HSP90AB1CYP19A1 | |
| SCHEMBL4398308 | 0.83 | CYP11B1 (0.49) | CYP11B1CYP11B2AGTR2CYP19A1 | |
| SCHEMBL4392534 | 0.82 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL13848456 | 0.82 | AGTR2 (0.44) | CYP11B1CYP11B2AGTR2CYP19A1 | |
| SCHEMBL4378118 | 0.80 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL28704117 | 0.78 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL13847779 | 0.76 | HSP90AA1 (0.43) | CYP11B1CYP11B2HSP90AA1HSP90AB1CYP19A1 | |
| SCHEMBL4377799 | 0.76 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1 | |
| SCHEMBL28702735 | 0.76 | HSP90AA1 (0.46) | CYP11B1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |