Chalcone

Chalcone

SCHEMBL4385453

O=C(C=Cc1ccccc1)c1ccccc1.O=C(O)C=Cc1ccccc1

nearest known ligand 0.88

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 10/20 0.88
MAPT P10636 6/20 0.88
MAOB P27338 5/20 0.88
LMNA P02545 2/20 0.88
BCHE P06276 2/20 0.88
TNFRSF1A P19438 2/20 0.88
PLIN1 O60240 1/20 0.88
ACHE P22303 1/20 0.88
RECQL P46063 1/20 0.88
PLIN5 Q00G26 1/20 0.88
ABHD5 Q8WTS1 1/20 0.88
HDAC3 O15379 3/20 0.76
HDAC4 P56524 3/20 0.76
HDAC1 Q13547 3/20 0.76
HDAC7 Q8WUI4 3/20 0.76
HDAC2 Q92769 3/20 0.76
HDAC10 Q969S8 3/20 0.76
HDAC11 Q96DB2 3/20 0.76
HDAC8 Q9BY41 3/20 0.76
HDAC6 Q9UBN7 3/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chalcone SCHEMBL4385450 1.00 CYP1B1 (0.88) CYP1B1MAPTMAOBLMNABCHE
SCHEMBL6881035 0.96 CYP1B1 (0.81) CYP1B1MAPTMAOBLMNABCHE
SCHEMBL25193884 0.96 CYP1B1 (0.81) CYP1B1MAPTMAOBLMNABCHE
SCHEMBL25202483 0.96 CYP1B1 (0.81) CYP1B1MAPTMAOBLMNABCHE
SCHEMBL25214545 0.96 CYP1B1 (0.81) CYP1B1MAPTMAOBLMNABCHE
SCHEMBL5196586 0.94 CYP1B1 (0.78) CYP1B1MAPTMAOBLMNABCHE
SCHEMBL5196588 0.94 CYP1B1 (0.78) CYP1B1MAPTMAOBLMNABCHE
SCHEMBL27541712 0.94 CYP1B1 (0.78) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL27581 0.94 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL29396001 0.94 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090252890-A1 METHOD FOR PRODUCING ANISOTROPIC FILM NITTO DENKO CORPORATION (JP) 2009-10-08 US disclosed
CN-100489574-C Method for producing anisotropic film NITTO DENKO CORP (JP) 2009-05-20 CN disclosed
US-20070054065-A1 Method for producing anisotropic film NITTO DENKO CORPORATION (JP) 2007-03-08 US disclosed
US-20060210709-A1 Method for producing anisotropic film NITTO DENKO CORPORATION (JP) 2006-09-21 US disclosed
CN-1813206-A Method for producing anisotropic film NITTO DENKO CORP (JP) 2006-08-02 CN disclosed
CN-1813205-A Method for producing anisotropic film NITTO DENKO CORP (JP) 2006-08-02 CN disclosed
EP-1666928-A1 METHOD FOR PRODUCING ANISOTROPIC FILM NITTO DENKO CORPORATION (JP) 2006-06-07 EP disclosed
EP-1666929-A1 METHOD FOR PRODUCING ANISOTROPIC FILM NITTO DENKO CORPORATION (JP) 2006-06-07 EP disclosed